Sort   by:  
 Page size 
TranscriptomicsTranscription profiling of human 493-6 cells (human EBV-transformed B lymphocytes) were infected with a retrovirus that produces human Lin-28B or empty virus to identify Myc- and Lin-28B-responsive transcripts
In order to examine the consequences of Myc and Lin-28B induction on the transcriptome, P493-6 cells (human EBV-transformed B lymphocytes) were infected with a retrovirus that produces human Lin-28B or empty virus as a control. Gene expression profiles were then monitored in the high and low Myc sta...
ORGANISM(S): Homo sapiens 
2009-03-14 | E-GEOD-14302 | biostudies-arrayexpress
TranscriptomicsPromotion of oogenesis and embryogenesis in the C. elegans gonad by EFL-1/DPL-1(E2F)does not require LIN-35(pRB)
Microarray-based expression profiling of dissected gonads from efl-1, dpl-1 and lin-35 mutants reveals that EFL-1 and DPL-1 promote expression of an extensively overlapping set of target genes, consistent with the expectation that these two proteins function as a heterodimer. Regulatory regions ups...
ORGANISM(S): Caenorhabditis elegans 
2010-07-01 | E-GEOD-5071 | biostudies-arrayexpress
GenomicsIdentification of Transcription Factor LIN-13::GFP Binding Regions in Embryos
modENCODE_submission_2613 This submission comes from a modENCODE project of Michael Snyder. For full list of modENCODE projects, see http://www.genome.gov/26524648 Project Goal: We are identifying the DNA binding sites for 300 transcription factors in C. elegans. Each transcription factor gene is ta...
ORGANISM(S): Caenorhabditis elegans 
2011-02-18 | E-GEOD-25804 | biostudies-arrayexpress
GenomicsIdentification of Transcription Factor LIN-15B::GFP Binding Regions in L3
modENCODE_submission_2610 This submission comes from a modENCODE project of Michael Snyder. For full list of modENCODE projects, see http://www.genome.gov/26524648 Project Goal: We are identifying the DNA binding sites for 300 transcription factors in C. elegans. Each transcription factor gene is ta...
ORGANISM(S): Caenorhabditis elegans 
2011-02-18 | E-GEOD-25802 | biostudies-arrayexpress
GenomicsIdentification of Transcription Factor LIN-11::GFP Binding Regions in L2
modENCODE_submission_2429 This submission comes from a modENCODE project of Michael Snyder. For full list of modENCODE projects, see http://www.genome.gov/26524648 Project Goal: We are identifying the DNA binding sites for 300 transcription factors in C. elegans. Each transcription factor gene is ta...
ORGANISM(S): Caenorhabditis elegans 
2011-02-18 | E-GEOD-25782 | biostudies-arrayexpress
TranscriptomicsChromosome-biased binding and gene regulation by the C. elegans DRM complex
This SuperSeries is composed of the following subset Series: GSE28494: Germline and embryo gene expression of wild-type vs. mutants in lin-54, a component of the C. elegans DRM complex GSE28852: Chromosome-biased binding and gene reguation by the C. elegans DRM complex [ChIP-chip] Refer to individua...
ORGANISM(S): Caenorhabditis elegans 
2011-04-27 | E-GEOD-28853 | biostudies-arrayexpress
GenomicsIdentification of Transcription Factor LIN-39::GFP Binding Regions in L3
modENCODE_submission_2432 This submission comes from a modENCODE project of Michael Snyder. For full list of modENCODE projects, see http://www.genome.gov/26524648 Project Goal: We are identifying the DNA binding sites for 300 transcription factors in C. elegans. Each transcription factor gene is ta...
ORGANISM(S): Caenorhabditis elegans 
2011-02-18 | E-GEOD-25785 | biostudies-arrayexpress
TranscriptomicsDRM complex mutant lin-54 vs. H3K36 methyltransferase mutant mes-4 vs. lin-54; mes-4 double mutant vs. wild type C.elegans germline
Here we uncover antagonistic regulation of transcript levels in the germline of Caenorhabditis elegans hermaphrodites. The histone methyltransferase MES-4 marks genes expressed in the germline with methylated Lys36 on histone H3 (H3K36me) and promotes their transcription; MES-4 also represses genes ...
ORGANISM(S): Caenorhabditis elegans 
2013-11-05 | E-GEOD-52064 | biostudies-arrayexpress
TranscriptomicsChromosome-biased binding and gene reguation by the C. elegans DRM complex [ChIP-chip]
DRM is a conserved transcription factor complex that includes E2F/DP and pRB family proteins and plays important roles in development and cancer. Here we analyze genome-wide binding and function of the C. elegans DRM subunit LIN-54. We demonstrate that LIN-54 DNA-binding activity is required for th...
ORGANISM(S): Caenorhabditis elegans 
2011-04-27 | E-GEOD-28852 | biostudies-arrayexpress
TranscriptomicsGermline and embryo gene expression of wild-type vs. mutants in lin-54, a component of the C. elegans DRM complex
DRM is a conserved transcription factor complex that includes E2F/DP and pRB family proteins and plays important roles in development and cancer. Here we perform microarray expression profiling analysis of lin-54, a DNA-binding member of the DRM complex. To identify genes regulated by LIN-54 in soma...
ORGANISM(S): Caenorhabditis elegans 
2011-04-09 | E-GEOD-28494 | biostudies-arrayexpress
Sort   by:  
 Page size