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ProteomicsProtein Biomarker Discovery for Methicillin-sensitive, Heterogeneous Vancomycin-Intermediate, and Vancomycin-intermediate Staphylococcus aureus Strains using Label-Free Data-Independent Acquisition Proteomics
90 S. aureus isolates were analyzed for protein biomarker discovery, including MSSA, vancomycin-susceptible S. aureus (VSSA), hVISA, and VISA strains. Label-free data-independent acquisition proteomics was used to identify protein biomarkers that allow for discrimination among MSSA, hVISA, and VISA ...
ORGANISM(S): Staphylococcus Aureus (ncbitaxon:1280) 
2020-07-18 | MSV000085776 | MassIVE
ProteomicsTIHAMAC: Streamlined Tandem IMAC-HILIC Workflow for Simultaneous and High-Throughput Plant Phosphoproteomics and N-glycoproteomics Analysis
Protein post-translational modifications (PTMs) are pivotal molecular events in plant cells, encompassing processes such as protein folding and enzyme activation. Among these PTMs, N-glycosylation and phosphorylation hold particular importance, as they play essential roles in regulating plant growth...
ORGANISM(S): Arabidopsis thaliana (Mouse-ear cress) 
2024-04-03 | PXD047065 | Pride
N-glycoproteomics Hilic Arabidopsis thaliana Imac Aba signaling Phosphoproteomics 
TranscriptomicsPosterior brain organoids multi-omics atlas
Here, we generated multiome (coupled scRNA-seq and scATAC-seq) data over a time course of mid- and hindbrain organoid development to map cell composition and explore the regulatory mechanisms underlying cell type maturation. The dataset incorporates 5 time points from day 7 to day 120 from 3 human i...
ORGANISM(S): Homo sapiens 
2026-03-17 | E-MTAB-15659 | biostudies-arrayexpress
TranscriptomicsscRNA-seq of posterior brain organoid morphogen screen
To pattern novel posterior brain regions, we used a multiplexed morphogen screen with a single-cell sequencing readout to test 48 concentrations and combinations of 10 morphogens involved in brain patterning. This screen revealed the emergence of regions harboring under-represented cell types, such ...
ORGANISM(S): Homo sapiens 
2026-03-16 | E-MTAB-15660 | biostudies-arrayexpress
UnknownAcute effects of dietary phosphorus intake on markers of mineral metabolism in hemodialysis patients: post hoc analysis of a randomized crossover trial.
Not available
S-EPMC7808738 | biostudies-literature
TranscriptomicsNgn2 induces diverse neuronal lineages from human pluripotency
Human neurons engineered from induced pluripotent stem cells (iPSCs) through Neurogenin 2 (Ngn2) overexpression are widely used to study neuronal differentiation mechanisms and to model neurological diseases. However, the differentiation paths and heterogeneity of emerged neurons have not been fully...
ORGANISM(S): Homo sapiens 
2021-08-05 | E-MTAB-10632 | biostudies-arrayexpress
TranscriptomicsscRNA-seq CRISPR screening of human posterior brain organoids
We used a pooled, multiplexed CRISPR/Cas9 gene knock-out (KO) experiment with single-cell transcriptomic readout to perturb and validate selected TF regulomes . We designed gRNAs and generated a pooled lentiviral library targeting 12 TFs with specific midbrain or hindbrain expression or high regulat...
ORGANISM(S): Homo sapiens 
2026-03-17 | E-MTAB-15826 | biostudies-arrayexpress
UnknownAssociation study between novel CYP26 polymorphisms and the risk of betel quid-related malignant oral disorders.
Not available
S-EPMC4369936 | biostudies-literature
UnknownKnockout of ho-1 protects the striatum from ferrous iron-induced injury in a male-specific manner in mice.
Not available
S-EPMC4873828 | biostudies-literature
UnknownOverexpression of the Arabidopsis and winter squash superoxide dismutase genes enhances chilling tolerance via ABA-sensitive transcriptional regulation in transgenic Arabidopsis.
Not available
S-EPMC6866689 | biostudies-literature
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