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MetabolomicsFunctional Characterization of the Lin28/let-7 Circuit During Forelimb Regeneration in Ambystoma mexicanum and Its Influence on Metabolic Reprogramming
The axolotl (Ambystoma mexicanum) is a caudate amphibian, which has an extraordinary ability to restore a wide variety of damaged structures by a process denominated epimorphosis. While the origin and potentiality of progenitor cells that take part during epimorphic regeneration are known to ...
2021-11-04 | MTBLS1708 | MetaboLights
TranscriptomicsEndometriosis: Normal endometrial stromal cells and endometriotic stromal cells
Gene expression profiling of primary stromal cell cultures isolated from human endometrium and ovarian endometriosis. Samples are derived from the endometrium of 6 healthy patients and the endometriomas of 6 diseased patients. The results indicate the gene expression differences between these two ce...
ORGANISM(S): Homo sapiens 
2014-08-01 | E-GEOD-58178 | biostudies-arrayexpress
UnknownComparative study of joint bioinformatics analysis of underlying potential of 'neurimmiR', miR-212-3P/miR-132-3P, being involved in epilepsy and its emerging role in human cancer.
Not available
S-EPMC5522300 | biostudies-literature
ProteomicsEnhanced Proteomic Coverage in Tissue Microenvironment by Immune Cell Subtype Library-assisted DIA-MS
The objective of the protject is to develop an immune cell-enrich library-assisted DIA method that enables the comprehensive identification and quantification of immunological proteins from micro-scale samples with high sensitivity. In the project, six immune cell subtype-specific libraries includin...
ORGANISM(S): Mus Musculus (mouse) 
2025-01-18 | PXD048670 | JPOST Repository
TranscriptomicsInvestigating GPR34 expression regulation using whole transcriptome sequencing of spleens and dendritic cells from wildtype and GPR34 knockout mice
Naive spleens as well as naive and LPS-treated dendritic cells from wildtype and GPR34-/- mice were sequenced to integrate expression profiles with protein interaction networks and find functional modules that are affected by GPR34 Expression profiles of dendritic cells and whole spleens were genera...
ORGANISM(S): Mus musculus 
2016-03-02 | E-GEOD-68155 | biostudies-arrayexpress
TranscriptomicsCEA_SGF:E00009#switch_lympho_mega
we analyzed the gene expression profile of newly produced transgenic bone marrow subpopulations and compared it to the expression patterns obtained from cells isolated from wild type mice at different stages of the hematopoietic differentiation process. These populations were enriched in HSC, CMP, C...
ORGANISM(S): Mus musculus 
2010-06-05 | E-GEOD-1289 | biostudies-arrayexpress
TranscriptomicsCEA_SGF:E00008#transgenic_IIb-tk
To investigate genes that are involved in hematopoietic cells production in vivo, we used microarray technology combined with a transgenic mouse model IIb-tk previously developed in our laboratory (Tropel et al., 1997). In these mice, the promoter region of the murine CD41 (GPIIb) gene was used to t...
ORGANISM(S): Mus musculus 
2010-06-09 | E-GEOD-1290 | biostudies-arrayexpress
UnknownExosomal miR-543 Inhibits the Proliferation of Ovarian Cancer by Targeting IGF2.
Not available
S-EPMC8983272 | biostudies-literature
UnknownPI3K/AKT/mTOR signaling transduction pathway and targeted therapies in cancer.
Not available
S-EPMC10436543 | biostudies-literature
TranscriptomicsT cell acute leukaemia development and chemo-resistance are mediated by dynamic interactions with heterogeneous bone marrow microenvironments.
It is widely accepted that complex interactions between cancer cells and their surrounding microenvironment contribute to disease development, chemo-resistance and disease relapse. In light of this observed interdependency, novel therapeutic interventions that target specific cancer stroma cell line...
ORGANISM(S): Homo sapiens 
2016-07-01 | E-MTAB-4889 | biostudies-arrayexpress
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