Sort   by:  
 Page size 
TranscriptomicsExpression data from WT, HEB-KO and E2A-KO LY6D- CLP cells
The E-protein transcription factors E2A and HEB play important roles at several stages of hematopoiesis. However, the exact mechanism for theire action and the main targets in the LY6D negative common lymphoid progentior (CLP) compartment remains unknown. By adressing this question, we will gain imp...
ORGANISM(S): Mus musculus 
2011-11-22 | E-GEOD-27402 | biostudies-arrayexpress
TranscriptomicsA global network of transcription factors, involving E2A, EBF1 and FOXO1, that orchestrates the B cell fate
It is now established that the transcription factors E2A, EBF1 and FoxoM-BM- 1 play critical roles in B cell development. Here we show that E2A and EBF1 bound regulatory elements present in the Foxo1 locus. E2A and EBF1 as well as E2A and Foxo1, in turn, were wired together by a vast spectrum of cis...
ORGANISM(S): Mus musculus 
2010-06-12 | E-GEOD-21978 | biostudies-arrayexpress
TranscriptomicsmicroRNA profiles of hematopoietic derivatives
Hematopoietic stem cells (HSCs) can regenerate the entire hematopoietic system in vivo, providing the most relevant criteria to measure candidate HSCs derived from human embryonic stem cell (hESC) or induced pluripotent stem cell (hiPSC) sources. Here, we show that unlike primitive hematopoietic cel...
ORGANISM(S): Homo sapiens 
2012-02-18 | E-GEOD-35923 | biostudies-arrayexpress
OtherAssessment of a method to characterize antibody selectivity and specificity for use in immunoprecipitation.
Data from ProteomeXchange, PXD ID: PXD002534. File: GR_130129_20_OT3_NT_L3MBTL2_FAB_31_G11_2_HEK293.mzXML. Published as part of Nat Methods. 2015 Jun 29 . From the Abstract: {{i}} ... We describe a mass spectrometry-based standard operating procedure for scoring immunoprecipitation antibody quality...
ORGANISM(S): Homo_sapiens_viruses, Human_female 
GPM32320016573 | GPMDB
Resource Reanalysis 
OtherQuantitative phosphoproteomics reveals pathways for coordination of cell growth and division by the fission yeast DYRK kinase Pom1
Data from ProteomeXchange, PXD ID:PXD001649 . File: o53292.mzml. Published as part of Mol Cell Proteomics. 2015 Feb 26 . From the Abstract: {{i}} ... Here, we sought to determine the phosphorylation targets of Pom1 kinase activity by SILAC-based phosphoproteomics. We defined a set of high-confidenc...
ORGANISM(S): S_pombe 
GPM32320013881 | GPMDB
Resource Reanalysis 
TranscriptomicsMicroRNA expression in lymphoma lines
MicroRNAs from lymphoma and leukemia cell lines with or without the 13q31 amplicon were quantitated using a custom microarray platform. 5ug total RNA from each line was labeled with cy3 and hybridized to a microarray that contains probes to 238 mouse and human mature microRNAs. Four data sets per ...
ORGANISM(S): Homo sapiens 
2010-06-10 | E-GEOD-2399 | biostudies-arrayexpress
GenomicsMolecular Genetic Studies of Developmental Brain Disorders

Study 1
2R01-NS050375 (PI: DOBYNS, William B.)
The genetic basis of mid-hindbrain malformations
Our general goal for this project is to advance our understanding of human developmental disorders that involve the brainstem and cerebellum - brain structures derived from the embryoni...

phs000455.v1.p1 | EGA
UnknownGenetic insights into biological mechanisms governing human ovarian ageing.
Not available
S-EPMC7611832 | biostudies-literature
UnknownBurden of 375 diseases and injuries, risk-attributable burden of 88 risk factors, and healthy life expectancy in 204 countries and territories, including 660 subnational locations, 1990-2023: a systematic analysis for the Global Burden of Disease Study 2023.
Not available
S-EPMC12535840 | biostudies-literature
UnknownGlobal, regional, and national trends in routine childhood vaccination coverage from 1980 to 2023 with forecasts to 2030: a systematic analysis for the Global Burden of Disease Study 2023.
Not available
S-EPMC12338332 | biostudies-literature
Sort   by:  
 Page size