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UnknownLncRNA Airn maintains LSEC differentiation to alleviate liver fibrosis via the KLF2-eNOS-sGC pathway.
Not available
S-EPMC9520944 | biostudies-literature
TranscriptomicsPreactivation of the interferon signaling in liver is correlated with non-response to interferon alpha therapy in patients chronically infected with hepatitis B virus
To screen the differentially expressed genes between responders(Rs) and nonresponders(NRs) in CHB patients treated with IFN-α, and to explore the molecular basis for treatment failure.Expression profiling was performed on percutaneous needle liver biopsy specimens taken before therapy.Gene expressio...
ORGANISM(S): Homo sapiens 
2011-03-01 | E-GEOD-27555 | biostudies-arrayexpress
ProteomicsIntegrative Proteome and Lysine Acetylation Analyses of Subcutaneous and Visceral Adipose Tissues in People with Metabolically Unhealthy Obesity
Adipose tissue is critical in the development of Metabolically unhealthy obesity (MUO). This study aimed to investigate the different responses and regulations of subcutaneous (SA) and visceral adipose tissue (VA) to MUO by integrative proteome and lysine acetylation (Kac) analyses. This study signi...
ORGANISM(S): Homo Sapiens 
PXD056800 |
Genomicsena-DATASET-BCCA-13-11-2014-22:09:20:907-954 - samples
Dynamics of genomic clones in breast cancer patient xenografts at single cell resolution
EGAD00001001066 | EGA
GenomicsDynamics of genomic clones in breast cancer patient xenografts at single cell resolution
Human cancers, including breast cancers, are comprised of clones differing in mutation content that evolve dynamically in space and time following principles of Darwinian evolution, underpinning important emergent features such as drug resistance and metastasis. Human breast cancer xenoengraftment i...
EGAS00001000952 | EGA
GenomicsBC Cancer, part of the Provincial Health Services Authority, Technology Development Office, Data Access Committee (PHSA TDO DAC)
Access to data generated by BCCA is made available by completing the data access agreement for review by the data access committee and will be granted to qualified investigators for appropriate use.
EGAC00000000011 | EGA
ProteomicsIntegrated proteomics and metabolomic analyses reveal the accumulation mechanism of bioactive components in Polygonatum odoratum
Polygonatum odoratum (MILL.) DRUCE is rich in bioactive components with high medicinal value. To maximize the clinical benefits, it is of great significance to efficiently extract key bioactive components from appropriate growth stages in which they are most abundant. In this study, we analyzed the ...
ORGANISM(S): Polygonatum Odoratum 
2024-12-14 | PXD058887 |
ProteomicsSuccinylationin V alginolyticus virulence
In this project successfully identified a total of 2082 succinylation sites matched with 671 proteins in V. alginolyticus.
ORGANISM(S): Vibrio Alginolyticus 40b 
2020-12-15 | PXD023153 |
ProteomicsCircular RNA circBNC2 regulates epithelial cell G2-M arrest to prevent fibrotic maladaptive repair
Epithelial cells arrested in G2/M phase of the cell cycle after injury is a key checkpoint for determining the wound-healing to either normal cell proliferation or fibrosis. The mechanism that regulates the fibrogenic response after injury is not well understood. Here, we identified a kidney- and li...
ORGANISM(S): Homo Sapiens 
PXD033284 |
ProteomicsAntifungal potential of naphthoquinone derivatives: Screening of shikonin-based compounds and mechanistic insights into 5,8-dihydroxy-1,4-naphthoquinone against Candida albicans in vitro and in vivo
These data present the mass spectrometry results from the proteomic profiling of PNP-02 against Candida albicans
ORGANISM(S): Candida Albicans 
2026-01-28 | PXD073742 |
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