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ProteomicsiTRAQ-based analysis of muscle mitochondria isolated from LONP1-mKO mice
This experiment was conducted to identify the mitochondrial protein changes in the presence and absence of LONP1 in skeletal muscle. The following abstract from the submitted manuscript describes the major findings of this work.Disuse-associated loss of muscle LONP1 impairs mitochondrial quality and...
ORGANISM(S): Mus musculus (Mouse) 
2022-01-05 | PXD029722 | Pride
Mouse Skeletal muscle 
TranscriptomicsMicroRNA signatures in human cervical cancer
Our study investigates miRNAs might play a role in the pathogenesis of cervical cancer and identify altered miRNA gene methylation as a possible epigenetic mechanism involved in their aberrant expression. Cervical cancer cells were seeded at low density and cultured for 48 h. Experimental groups wer...
ORGANISM(S): Homo sapiens 
2011-10-10 | E-GEOD-32724 | biostudies-arrayexpress
TranscriptomicsFetal lung development
Fetal lung development is a complex biological process, which involves temporal and spatial regulations of many genes. To understand molecular mechanisms of this process, we investigated gene expression profiling of lungs at gestational day 18, 19, 20, 21, new born, and adult rats using in-house rat...
ORGANISM(S): Rattus norvegicus 
2010-07-01 | E-GEOD-3302 | biostudies-arrayexpress
TranscriptomicsArsenic-induced Changes in L2 Cells
Arsenic is a carcinogen that is known to induce cell transformation and tumor formation. Although studies have been performed to examine the modulation of signaling molecules caused by arsenic exposure, the molecular mechanisms by which arsenic causes cancer are still unclear. We hypothesized that ...
ORGANISM(S): Rattus norvegicus 
2011-12-23 | E-GEOD-9790 | biostudies-arrayexpress
ProteomicsProteomics of SEMA5A, MT-ATP6, ZNF662, and KDM4C in zebrafish embryos
Proteomics of SEMA5A, MT-ATP6, ZNF662, and KDM4C in zebrafish embryos
ORGANISM(S): Danio Rerio 
2024-02-05 | PXD049175 |
ProteomicsProteome analysis of Alpine Merino sheep skin reveals new insights into the mechanisms involved in regulating wool fiber diameter
Wool fiber is a textile material that is highly valued based on its diameter, which is crucial in de-termining its economic value. To analyze the molecular mechanisms regulating wool fiber diameter, we used a data-independent acquisition-based quantitative proteomics approach to analyze the skin pro...
ORGANISM(S): Ovis Aries 
PXD046045 |
ProteomicsGypenosides ameliorate high-fat diet-induced nonalcoholic fatty liver disease in mice by regulating lipid metabolism
Gypenosides is a traditional drug for the treatment of metabolic disorders. Recent studies have confirmed its anti-nonalcoholic fatty liver disease (NAFLD) effects, but the underlying mechanisms are still not fully understood. The purpose of this study was to explore the protective mechanism of gype...
ORGANISM(S): Mus Musculus 
2022-12-14 | PXD038829 |
ProteomicsTemporal proteomics characterization of COVID-19 patient sera
We enrolled 37 SARS-CoV-2 positive patients including 17 short course (SC) COVID-19 patients (twice viral RNA detection negative over 24 hrs) and 20 COVID-19 long course (LC) COVID-19 patients. We also included 35 SARS-CoV-2 negative patients as control group. We collected 224 inactive serum samples...
ORGANISM(S): Homo Sapiens 
PXD035471 |
ProteomicsIdentification of key factors in cartilage tissue during the progression of osteoarthritis using a non-targeted metabolomics strategy
This work used non-targeted metabolomics and screened out differential metabolites and metabolic pathways, providing a reliable theoretical basis for further study of specific markers and their specific pathways in the progression of OA.
ORGANISM(S): Homo Sapiens 
PXD041287 |
UnknownNew progress in HBV control and the cascade of health care for people living with HBV in China: evidence from the fourth national serological survey, 2020.
Not available
S-EPMC11419793 | biostudies-literature
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