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UnknownSpeedy A governs non-homologous XY chromosome desynapsis as a unique prerequisite for XY loop-axis organization
Not available
S-SCDT-10_1038-S44318-025-00528-8 | biostudies-other
MetabolomicsComparative metabolomics reveals serum metabolites changes in goats during different developmental stages

Goats can provide meat, milk and skins for humans and are livestock with high economic benefits. However, despite their economic significance, the comprehensive analysis of goats' serum metabolic profile and its intricate alterations throughout their developmental journey remains conspicuously ab...

2024-06-04 | MTBLS8944 | MetaboLights
ProteomicsProteomics of SEMA5A, MT-ATP6, ZNF662, and KDM4C in zebrafish embryos
Proteomics of SEMA5A, MT-ATP6, ZNF662, and KDM4C in zebrafish embryos
ORGANISM(S): Danio Rerio 
2024-02-05 | PXD049175 |
ProteomicsHuman T21 Amniocyte samples LC-MS/MS
Amniocyte samples of T21 males, T21 females, CN males, and CN females were collected by amniocentesis. The quantitative value of the peptide corresponding to each sample was determined through quantitative analysis by mass spectrometry.
ORGANISM(S): Homo Sapiens 
PXD032883 |
ProteomicsIdentification of key factors in cartilage tissue during the progression of osteoarthritis using a non-targeted metabolomics strategy
This work used non-targeted metabolomics and screened out differential metabolites and metabolic pathways, providing a reliable theoretical basis for further study of specific markers and their specific pathways in the progression of OA.
ORGANISM(S): Homo Sapiens 
PXD041287 |
ProteomicsPhosphoproteomics reveals that cinobufotalin promotes intrahepatic cholangiocarcinoma cell apoptosis by activating the ATM/CHK2/p53 signaling pathway
In this study, we found that CB inhibited ICC cell proliferation and promoted cell apoptosis. By using phosphoproteomics, we found significant changes in the proteome and phosphorylome associated with DNA damage and apoptosis in response to CB treatment. Further investigations demonstrated that CB i...
ORGANISM(S): Homo Sapiens 
2022-06-20 | PXD034717 |
ProteomicsChaperonin TRiC bridges radial spokes for folding proteins locally translated in mammalian sperm flagella
As animals evolved from external to internal fertilization, sperm flagella, which once transiently propelled sperm in water to reach nearby eggs, developed to beat for days or even longer within the female reproductive tract. How flagella were remodeled accordingly remains unclear. Unlike externally...
ORGANISM(S): Bos Taurus 
PXD067693 |
ProteomicsTargeting WTX-P54nrb Phase Separation Sensitizes Chemotherapy in Gastric Cancer
To provide insights into any distinctions between the cellular functions of WTX-S and WTX-L, we defined their protein interaction networks by performing liquid chromatography–tandem MS of affinity-purified protein complexes.
ORGANISM(S): Homo Sapiens 
PXD057127 |
ProteomicsIdentification of a novel bile marker Clusterin and a public online prediction platform based on deep learning for Cholangiocarcinoma
Identification of a novel bile marker Clusterin and a public online prediction platform based on deep learning for Cholangiocarcinoma
ORGANISM(S): Homo Sapiens 
2023-07-13 | PXD043745 |
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