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TranscriptomicsIntegrated genomic and gene expression profiling identifies two major gene/genomic circuits operating in urothelial carcinoma
This SuperSeries is composed of the following subset Series: GSE32535: Integrated genomic and gene expression profiling identifies two major gene/genomic circuits operating in urothelial carcinoma (genomic) GSE32548: Integrated genomic and gene expression profiling identifies two major gene/genomic ...
ORGANISM(S): Homo sapiens 
2012-06-17 | E-GEOD-32549 | biostudies-arrayexpress
TranscriptomicsA Molecular Taxonomy of Urothelial Carcinoma
Even though urothelial cancer (UC) is the fourth common tumor type among males, progress in treatment development has been deficient. Pathological assessment provides the urologists with only a broad classification, complicated by frequent disagreement among pathologist and the co-existence of diffe...
ORGANISM(S): Homo sapiens 
2012-05-23 | E-GEOD-32894 | biostudies-arrayexpress
TranscriptomicsDetailed analysis of 6p and 1q amplifications in urothelial carcinoma reveals SOX4 as an auxiliary target on 6p, and BCL9, CHDL1, MCL1, SETDB1, and HIF1B as putative targets on 1q.
Background: Previous array CGH analyses have revealed several recurring genomic alterations in urothelial carcinoma. The most common genomic amplifications occur at 6p22 and 1q21-24. The main target gene at 6p22 is believed to be E2F3. This gene is frequently co-amplified with CDKAL1 and SOX4 and th...
ORGANISM(S): Homo sapiens 
2013-08-30 | E-GEOD-40938 | biostudies-arrayexpress
TranscriptomicsIntegrated genomic and gene expression profiling identifies two major gene/genomic circuits operating in urothelial carcinoma (gene expression)
Genomic and gene expression profiling identifies two major gene/genomic circuits operating in urothelial carcinoma 131 primary bladder cancer tumor samples were analyzed on Illumina gene expression Bead Arrays.
ORGANISM(S): Homo sapiens 
2012-06-17 | E-GEOD-32548 | biostudies-arrayexpress
TranscriptomicsIntegrated genomic and gene expression profiling identifies two major gene/genomic circuits operating in urothelial carcinoma (genomic)
Genomic and gene expression profiling identifies two major gene/genomic circuits operating in urothelial carcinoma 146 primary bladder cancer tumor samples were analyzed on BAC array containing ~32 000 BAC clones. Arrays were produced at the Swegene Centre for Integrative Biology at Lund University ...
ORGANISM(S): Homo sapiens 
2012-06-17 | E-GEOD-32535 | biostudies-arrayexpress
TranscriptomicsNormalization of Illumina Infinium whole-genome SNP data improves copy number estimates and allelic intensity ratios
Illumina Infinium whole genome genotyping (WGG) arrays are increasingly being applied in cancer genomics to study gene copy number alterations and allele-specific aberrations such as loss-of-heterozygosity (LOH). Methods developed for normalization of WGG arrays have mostly focused on diploid, norma...
ORGANISM(S): Homo sapiens 
2008-10-04 | E-GEOD-11977 | biostudies-arrayexpress
UnknownA Bayesian General Linear Modeling Approach to Cortical Surface fMRI Data Analysis.
Not available
S-EPMC7556728 | biostudies-literature
TranscriptomicsDNA methylation analyses of urothelial carcinoma reveal distinct epigenetic subtypes and an association between gene copy number and methylation status
We assessed DNA methylation and copy number status of 27,000 CpGs in 149 urothelial carcinomas and integrated the findings with gene expression and mutation data. Methylation was associated with gene expression for 1,332 CpGs, of which 26% showed positive correlation with expression, i.e., high meth...
ORGANISM(S): Homo sapiens 
2012-08-31 | E-GEOD-33510 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of human skeletal muscle from males with type 2 diabetes to identify genes involved in oxidative phosphorylation
DNA microarrays can be used to discover gene expression changes characteristic of human disease. This is challenging, however, when relevant differences are subtle at the level of individual genes. We introduce an analytical strategy, Gene Set Enrichment Analysis, designed to detect modest but coord...
ORGANISM(S): Homo sapiens 
2007-07-17 | E-CBIL-30 | biostudies-arrayexpress
TranscriptomicsAstrocytes’ response to Flunarizine combined with irradiation
Bulk RNAseq analysis of mRNA content of human primary astrocytes irradiated with 10 Gy and/or treated with Flunarizine 10uM.
ORGANISM(S): Homo sapiens 
2025-08-19 | E-MTAB-15215 | biostudies-arrayexpress
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