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ProteomicsoptiPRM: A targeted immunopeptidomics LC-MS workflow with ultra-high sensitivity for the detection of mutation-derived tumor neoepitopes from limited input material
Personalized cancer immunotherapies such as vaccines and T cell receptor (TCR)-transgenic T cells rely on the presentation of tumor-specific peptides by human leukocyte antigen (HLA) class I molecules to cytotoxic T cells. Such neoepitopes can for example arise from somatic mutations and their ident...
ORGANISM(S): Homo sapiens (Human) 
2024-08-09 | PXD043542 | Pride
Immunopeptidomics Prm Lc-ms Targeted ms 
UnknownRegulatory dynamics of gene expression in the developing male gametophyte of Arabidopsis.
Not available
S-EPMC10363097 | biostudies-literature
ProteomicsRegulatory dynamics of gene expression in the developing male gametophyte of Arabidopsis
Sexual reproduction in angiosperms requires the production and delivery of two male gametes by a three-celled haploid male gametophyte. This demands synchronised gene expression in a short developmental window to ensure double fertilization and seed set. While transcriptomic changes in developing po...
ORGANISM(S): Arabidopsis thaliana (Mouse-ear cress) 
2022-11-01 | PXD033305 | Pride
Arabidopsis Ler-0 Lc-ms Male gametophyte Microgametogenesis Col-0 Proteome Rna-seq 
UnknownGenome-wide linkage analysis is a powerful prenatal diagnostic tool in families with unknown genetic defects.
Not available
S-EPMC3598323 | biostudies-literature
UnknownMediMer: a versatile do-it-yourself peptide-receptive MHC class I multimer platform for tumor neoantigen-specific T cell detection.
Not available
S-EPMC10794645 | biostudies-literature
UnknownFaulty initiation of proteoglycan synthesis causes cardiac and joint defects.
Not available
S-EPMC3135799 | biostudies-literature
Genomicsena-DATASET-RTL-11-03-2015-12:07:49:303-16 - samples
Whole genome sequencing was performed with DNA extracted from fresh-frozen tumor and normal material. Short insert DNA libraries were prepared with the TruSeq DNA PCRfree sample preparation kit (Illumina) for paired-end sequencing at a minimum read length of 2x100bp. Human DNA libraries were sequenc...
EGAD00001001273 | EGA
UnknownClinical use and predictors of outcome in venoarterial extracorporeal membrane (VA ECMO): insights from VERGE (VA ECMO Registry of Germany).
Not available
S-EPMC12460512 | biostudies-literature
UnknownSymptoms, SARS-CoV-2 Antibodies, and Neutralization Capacity in a Cross Sectional-Population of German Children.
Not available
S-EPMC8522552 | biostudies-literature
GenomicsSCLC_SNP_6.0 - samples
SNP 6.0 arrays of small cell lung cancer
EGAD00010000558 | EGA
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