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TranscriptomicsEffects of PKC412 on gene expression and link to physiological effects in zebrafish Danio rerio eleuthero-embryos
To identify molecular effects of the antineoplastic agent PKC412 (Midostaurin), we applied gene expression profiling in zebrafish using whole genome microarrays. Zebrafish eleuthero-embryos were exposed for 6 dpf to nominal levels of 2 μg/L and 40 μg/L PKC412. Among the 259 and 511 altered transcrip...
ORGANISM(S): Danio rerio 
2011-07-22 | E-GEOD-23156 | biostudies-arrayexpress
TranscriptomicsEffects of diazepam on gene expression and link to physiological effects in different life stages in zebrafish Danio rerio
We applied zebrafish whole genome microarrays to identify molecular effects of diazepam, a neuropharmaceutical encountered in wastewater-contaminated environments, and to elucidate its neurotoxic mode of action. Behavioral studies were performed to analyze for correlations between altered gene expre...
ORGANISM(S): Danio rerio 
2011-07-22 | E-GEOD-23157 | biostudies-arrayexpress
UnknownPaternal heat exposure causes DNA methylation and gene expression changes of Stat3 in Wild guinea pig sons.
Not available
S-EPMC4769883 | biostudies-literature
UnknownOxidising agents in sub-arc mantle melts link slab devolatilisation and arc magmas.
Not available
S-EPMC6115406 | biostudies-literature
UnknownInfluence of CRHR1 Polymorphisms and Childhood Abuse on Suicide Attempts in Affective Disorders: A GxE Approach.
Not available
S-EPMC5933260 | biostudies-literature
ProteomicsStructural study of human MRE11-RAD50-NBS1 (MRN) complex by crosslinking mass spectrometry
A chemical crosslinking-mass spectrometry (CX-MS) experiment was performed to study the structure of the human MRN complex in the presence of ATM and DNA.
ORGANISM(S): Homo sapiens (Human) 
2025-08-13 | PXD067324 | Pride
Cx-ms Mrn complex 
MetabolomicsOn-line untargeted metabolomics monitoring of an Escherichia coli succinate fermentation process
The real-time monitoring of metabolites (RTMet) is instrumental for the industrial production of biobased fermentation products. This study shows the first application of untargeted on-line metabolomics for the monitoring of undiluted fermentation broth samples taken automatically from a 5 L bioreac...
2023-04-26 | MTBLS5197 | MetaboLights
UnknownThe porphyrin center as a regulator for metal-ligand covalency and π hybridization in the entire molecule.
Not available
S-EPMC8579471 | biostudies-literature
ProteomicsComprehensive XL-MS reveals parallel orientation and versatile conformations of plant HOP2/MND1
The HOP2/MND1 heterodimer is essential for meiotic homologous recombination in plants and other eukaryotes, and promotes the repair of DNA double strand breaks. The HOP2/MND1 dimer forms via the central, split coiled coils (CC1 and CC2) present in both proteins, and the resulting complex contains se...
ORGANISM(S): Arabidopsis thaliana (Mouse-ear cress) 
2015-11-05 | PXD001538 | Pride
Xl hop2 mnd1 cross link 
UnknownTranslational control of myelin basic protein expression by ERK2 MAP kinase regulates timely remyelination in the adult brain.
Not available
S-EPMC4438130 | biostudies-literature
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