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ProteomicsQuantitative proteomics of human heart samples collected in vivo reveal the remodeled protein landscape of dilated left atrium without atrial fibrillation.
Genetic and genomic research has greatly advanced our understanding of heart disease; yet a comprehensive map of the protein landscape of living human hearts is still lacking. Here we set out to identify the molecular basis of functional differences between human cardiac chambers by comprehensive p...
ORGANISM(S): Homo sapiens (Human) 
2020-06-15 | PXD008722 | Pride
Heart Tissue Hypertrophy Biopsies Mitral valve disease Gwas Dilated cardiomyopathy Human 
ProteomicsQuantitative proteomics profiling determines the uniqueness of the sinus node
The sinus node is a collection of highly specialized cells that constitute the natural pacemaker activity of our heart. The protein expression landscape of the sinus node differs from the surrounding cardiac tissue, although it is primarily comprised of myocytes and fibroblasts like the rest of the ...
ORGANISM(S): Mus musculus (Mouse) 
2019-07-08 | PXD008736 | Pride
Pacemaker Heart Tissue Sinus node Mouse Conduction Lc-ms/ms 
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