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TranscriptomicsRequirement for Lis1 in normal and malignant hematopoietic stem cell renewal to investigate requirement for Lis1 in normal and malignant hematopoietic stem cell renewal
Adult Lis1+/+creER or Lis1f/fcreER mice were treated with tamoxifen for five consecutive days. Three days after the final tamoxifen administration, KLS (ckit+ Lin- Sca1+) bone marrow cells were FACS-sorted and total cellular RNAs were purified. RNAs were amplified, labeled, hybridized onto Affymetr...
ORGANISM(S): Mus musculus 
2014-02-02 | E-MEXP-3855 | biostudies-arrayexpress
ProteomicsLis1 dynein interactome dataset
Interactome study of Lis1 and dynein subunit DIC1 from mammalian cells
ORGANISM(S): Homo sapiens (Human) 
2025-11-13 | PXD058912 | Pride
Lis1 dynein 
ProteomicsLIS1 RNA binding orchestartes the mechanosensitive properties of embryonic stem cells in AGO2 dependent and independent ways.
LIS1 immunoprecipitation in nuclear and cytoplasmic fractions of LIS1 Floxed/-, OE and WT embryonic stem cells. To identify AGO2 dependent and independent interactions LIS1 was immunoprecipitated in AGO1-4 knockout and doxycycline induced AGO2 mouse embryonic stem cells.
ORGANISM(S): Mus musculus (Mouse) 
2023-07-20 | PXD033150 | Pride
Oe Dox.ago2 Ago1-4 ko Nuclear and cytoplasmic fractions Flox/- Wt Mouse embyonic stem cells Lis1 ip 
TranscriptomicsTransient knockdown of LIS1 results in seizures, differential gene expression and a neuronal migration disorder in developing zebrafish
Mutation or deletion of LIS1 (Lissencephaly-1) underlies classical lissencephaly, a migration disorder resulting in brain malformation, epilepsy and mental retardation. Orthologues for LIS1 genes (lis1a and lis1b) are ubiquitously expressed in developing zebrafish larvae, but the functional consequ...
ORGANISM(S): Danio rerio 
2013-06-15 | E-GEOD-47952 | biostudies-arrayexpress
ProteomicsLis1 in human cortical organoids
Lysate analysis of WT or Lis1-mutant human cortical organoids
ORGANISM(S): Homo sapiens (Human) 
2025-03-11 | PXD040813 | Pride
Organoids Cortex Lis1 
ProteomicsLis1 in human hippocampus organoids
Lysate analysis of WT or Lis1-mutant human hippocampus organoids
ORGANISM(S): Homo sapiens (Human) 
2025-03-11 | PXD040911 | Pride
Organoids Hippocampus Human Lis1 Lc-ms/ms 
UnknownTargeted mutagenesis of Lis1 disrupts cortical development and LIS1 homodimerization.
Not available
S-EPMC33485 | biostudies-literature
GenomicsHepatic loss of Lis1 leads to fatty liver and predisposes to tumorigenesis in mice
Hepatic loss of Lis1 leads to fatty liver and predisposes to tumorigenesis in mice
PRJNA422444 | ENA
UnknownNudC-like protein 2 regulates the LIS1/dynein pathway by stabilizing LIS1 with Hsp90.
Not available
S-EPMC2840461 | biostudies-literature
GenomicsLIS1 RNA-binding orchestrates the mechanosensitive properties of embryonic stem cells in AGO2-dependent and independent ways [1_MARS_seq_A]
LIS1 RNA-binding orchestrates the mechanosensitive properties of embryonic stem cells in AGO2-dependent and independent ways [1_MARS_seq_A]
PRJNA814672 | ENA
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