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Escherichia coli possesses >65 small proteins of <50 amino acids, many of which are uncharacterized. We have identified a new small protein, MntS, involved in manganese homeostasis. Manganese is a critical micronutrient, serving as an enzyme cofactor and protecting against oxidative stress. Yet mang...
ORGANISM(S): Escherichia coli str. K-12 substr. MG1655 
ddDT runs of peptides from four separate protease digestions. CID for z=2, ETD for z>=3
ORGANISM(S): Schizosaccharomyces Pombe (ncbitaxon:4896) 
2015-01-30 | MSV000079025 | MassIVE
Diffuse large B-cell lymphoma is a heterogenous malignancy that can arise de novo or can result from histologic transformation from indolent lymphomas. Considerable sequencing effort has been placed on determining the mutations that are common at the time of diagnosis in DLBCL but little is known ab...
In this study we used microarray analysis to reveal the gene expression profile of the hippocampal CA1 subregion, which was laser-capture microdissected one week after kainic acid (KA)-induced status epilepticus (SE) in postnatal day 21 (P21) rats. These rats are developmentally roughly comparable t...
ORGANISM(S): Rattus norvegicus 
3 hour nLC-MS/MS runs used to compare/combine CID/ETD/HCD spectra for peptides from four separate protease digesions.
2013-12-23 | MSV000078517 | MassIVE
S. pombe proteome digested separately by four proteases and analyzed with an LTQ-Orbitrap Velos with a data-dependent decision tree method.
2013-12-23 | MSV000078516 | MassIVE
Genome-wide DNA methylation was studied to determine the methylome map of lymphoid and myeoloid commitment from hematopoietic progenitors We used custom Nimblegen microarrays to determine the genome-wide DNA methylation in FACs purified mouse hematopoietic progeniors We isolated genomic DNA from mou...
ORGANISM(S): Mus musculus 
Background & Aims Patient-derived gastrointestinal organoids are powerful tools for studying human physiology and disease. However, generating organoids requires prompt isolation and culture of fresh tissue, which is labor and time intensive, placing restraints on basic and clinical research. For ex...
ORGANISM(S): Homo sapiens 
Abstract: Candida parapsilosis and Candida albicans are human fungal pathogens that belong to the CUG clade in the Saccharomycotina. In contrast to C. albicans, relatively little is known about the virulence properties of C. parapsilosis, a pathogen particularly associated with infections of prematu...
ORGANISM(S): Candida parapsilosis 
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