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TranscriptomicsRNA-sequencing of TGF-M-CM-^_1-driven gene expression in human kidney cell line
TGF-beta1 is the major cytokine driver of fibrotic scarring observed in diabetic nephropathy and other fibrosis-related diseases. RNA-sequencing offers the potential for more sensitive assessment of the TGF-M-CM-^_1-driven transcriptome. There were two treatment groups: vehicle, 48 hr TGFb1. Each tr...
ORGANISM(S): Homo sapiens 
2012-03-31 | E-GEOD-29660 | biostudies-arrayexpress
UnknownSexual and Reproductive Health Literacy, Misoprostol Knowledge and Use of Medication Abortion in Lagos State, Nigeria: A Mixed Methods Study.
Not available
S-EPMC8362169 | biostudies-literature
GenomicsEstablishment of regions of genomic activity during the Drosophila maternal-to-zygotic transition
A conspicuous feature of early animal development is the lack of transcription from the embryonic genome, and it typically takes several hours to several days (depending on the species) until widespread transcription of the embryonic genome begins. Although this transition is ubiquitous, relatively ...
ORGANISM(S): Drosophila melanogaster 
2014-10-16 | E-GEOD-58935 | biostudies-arrayexpress
UnknownKnock-out of 5-lipoxygenase in overexpressing tumor cells-consequences on gene expression and cellular function.
Not available
S-EPMC9842508 | biostudies-literature
UnknownAssociation of Cell-Free DNA Tumor Fraction and Somatic Copy Number Alterations With Survival in Metastatic Triple-Negative Breast Cancer.
Not available
S-EPMC5815405 | biostudies-literature
UnknownBTK inhibition limits B-cell-T-cell interaction through modulation of B-cell metabolism: implications for multiple sclerosis therapy.
Not available
S-EPMC8960592 | biostudies-literature
TranscriptomicsQuaking is a global regulator of muscle-specific alternative splicing in vertebrates [differentiation data]
This work provides the first evidence that Qk is a global regulator of splicing in vertebrates, defines a new splicing regulatory network in muscle, and suggests that overlapping splicing networks contribute to the complexity of changes in alternative splicing during differentiation. Alternative spl...
ORGANISM(S): Mus musculus 
2013-06-05 | E-GEOD-40956 | biostudies-arrayexpress
TranscriptomicsQuaking is a global regulator of muscle-specific alternative splicing in vertebrates [siRNA data]
This work provides the first evidence that Qk is a global regulator of splicing in vertebrates, defines a new splicing regulatory network in muscle, and suggests that overlapping splicing networks contribute to the complexity of changes in alternative splicing during differentiation. Alternative spl...
ORGANISM(S): Mus musculus 
2013-06-05 | E-GEOD-40961 | biostudies-arrayexpress
TranscriptomicsPhase I study of Veliparib in combination with Cisplatin and Vinorelbine for patients with advanced triple-negative breast cancer (TNBC) and/or BRCA mutation-associated breast cancer
PURPOSE: Preclinically, cisplatin is synergistic with vinorelbine and the poly(ADP-ribose) polymerase (PARP) inhibitor veliparib, and has anti-neoplastic activity in TNBC and BRCA mutation-associated breast cancer. This phase I study assessed veliparib with cisplatin and vinorelbine. PATIENTS AND M...
ORGANISM(S): Homo sapiens 
2015-09-09 | E-GEOD-72795 | biostudies-arrayexpress
UnknownThe BCL-2 family member BID plays a role during embryonic development in addition to its BH3-only protein function by acting in parallel to BAX, BAK and BOK
Not available
S-SCDT-EMBOJ-2021-110300 | biostudies-other
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