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ProteomicsTargeting MGAT4A-mediated N-glycosylation as a therapeutic strategy to inhibit glioblastoma stem cell invasion
Proteomic glycosylation mapping via mass spectrometry and co-immunoprecipitation assays elucidates the MGAT4A interaction with EGFR, catalyzing N-glycosylation at the EGFR N604 site.
ORGANISM(S): Homo sapiens (Human) 
2025-01-18 | PXD052176 | Pride
Human Cell N-glycoproteomics Label-free 
UnknownTargeting RPL23 restores chemosensitivity of cisplatin-resistant ovarian carcinoma by inhibiting EMT.
Not available
S-EPMC9206980 | biostudies-literature
ProteomicsCross-tissue deep profiling of redox proteome in obese mice
Cellular redox state, the balance between oxidation and reduction, is precisely regulated through cysteine thiol modification. In this study, we developed a novel method, in conjunction with directed data-independent acquisition (dDIA) for identifying and quantifying a substantial number of sulfhydr...
ORGANISM(S): Mus Musculus 
2025-07-15 | PXD066139 |
TranscriptomicsEvx1as and EVX1 knockouts by CRISPR
We report that long noncoding RNAs contribute to transcription and developmental process. Thousands of lncRNAs have been identified in the whole genome, and tend to located closely to protein-coding genes. To study position relationship between lncRNA and protein-coding genes, we classified all of l...
ORGANISM(S): Mus musculus 
2016-03-24 | E-GEOD-70419 | biostudies-arrayexpress
ProteomicsMAGL Targeted PROTAC Degrader Simultaneously Enhances P53 for Synergistic Treatment of Glioblastoma Stem Cell
This study focuses on the protein degradation effects of the MAGL inhibitor JZL184 and the newly synthesized MAGL-PROTAC on MAGL.
ORGANISM(S): Homo Sapiens 
2024-12-02 | PXD058506 |
MetabolomicsIdentification of Biomarkers Using Metabolomics: From Chronic Non-Atrophic Gastritis and Chronic Atrophic Gastritis to Gastric Cancer

Gastric cancer (GC) is a severe malignancy characterized by late diagnosis, poor prognosis and low survival rates. Its progression is often linked to chronic non-atrophic gastritis (CNAG) and chronic atrophic gastritis (CAG), which show atypical symptoms. Identifying biomarkers for CNAG, CAG and ...

2026-09-29 | MTBLS12186 | MetaboLights
ProteomicsProtein Lysine 43 Methylation by EZH1 Promotes AML1-ETO Transcriptional Repression
The MS data of Protein Lysine 43 Methylation by EZH1 Promotes AML1-ETO Transcriptional Repression Protein Lysine 43 Methylation by EZH1 Promotes AML1-ETO Transcriptional Repression
ORGANISM(S): Homo Sapiens 
2019-12-11 | PXD016712 |
ProteomicsProteotypic differences of follicular-patterned thyroid neoplasms
The diagnosis of follicular-patterned thyroid tumors such as follicular adenoma (FA), follicular thyroid carcinoma (FTC), and follicular variant of papillary thyroid carcinoma (FvPTC) remains challenging. This study aimed to explore the molecular differences among these three thyroid tumors by prote...
ORGANISM(S): Homo Sapiens 
2022-09-07 | PXD036553 |
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