Liu Liangchen L

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Unknown (7)
Metabolomics (1)
Proteomics (1)

Organisms

Mus musculus (1)

Repository

MetaboLights (1)
pride (1)

Tissue

Liver (1)

Technology Type

Mass spectrometry (1)
Bottom-up proteomics (1)
Data-dependent acquisition (1)
Mass Spectrometry (1)

Instrument Platform

Liquid Chromatography MS - negative - reverse phase (1)

Publication Date

2025 (2)

Metabolite Name

(5-L-Glutamyl)-L-Amino Acid (1)
(6R,S)-5, 10-Methylene-5,6,7,8-tetrahydrofolic acid (1)
(R)-3-Hydroxy myristic acid (1)
(S)-Leucic acid (1)
(¡À)10(11)-EpDPA (1)
(¡À)11(12)-EET (1)
(¡À)11-HETE (1)
(¡À)12(13)-DiHOME (1)
(¡À)13-HODE (1)
(¡À)14(15)-DiHET (1)
(¡À)17(18)-DiHETE (1)
(¡À)19(20)-DiHDPA (1)
(¡À)5(6)-DiHET (1)
(¡À)8(9)-DiHET (1)
(¡À)9(10)-DiHOME (1)
(¡À)9-HpODE (1)
1-(4-methylphenyl)-3-(2-pyridylthio)pyrrolidine-2,5-dione (1)
1-Methylguanosine (1)
10-Hydroxydecanoic acid (1)
11(E)-Eicosenoic Acid (1)
11(Z),14(Z)-Eicosadienoic Acid (1)
11-Ketoetiocholanolone (1)
11-keto Testosterone (CRM) (1)
12,13-EODE (1)
12-Hydroxydodecanoic acid (1)
12-epi Leukotriene B4 (1)
13,14-dihydro-15-keto Prostaglandin A2 (1)
13,14-dihydro-15-keto-tetranor Prostaglandin D2 (1)
13-Hpotre(R) (1)
16-Hydroxyhexadecanoic acid (1)

Release Date

2023 (2)
2020 (2)
2025 (1)
2024 (1)
2022 (1)

Lab affiliation

Department of Hepatology, Tianjin Medical University General Hospital, Tianjin, China (1)

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Multi-omics analysis reveals immune-metabolic dysregulation in DNASE1L3-deficient mouse liver

This study investigates the role of DNASE1L3 deficiency in hepatic immune and metabolic regulation. Using transcriptomics, proteomics, and metabolomics, we characterize changes in Kupffer cell polarization, ER stress, iron metabolism, and ferroptosis in DNASE1L3 knockout mice.'

2025-10-25 | MTBLS13057 | MetaboLights

TMT-Based Quantitative Proteomic Profiling of DNASE1L3-Deficient and Wild-Type Mouse Livers

This study investigates the impact of DNASE1L3 deficiency on hepatic immune–metabolic homeostasis using TMT-based quantitative proteomics. Liver tissues from 8-week-old wild-type (WT) and DNASE1L3 knockout (KO) mice were analyzed by LC-MS/MS. Differential protein expression and pathway enrichment an...

ORGANISM(S): Mus musculus (Mouse)

2025-11-17 | PXD068786 | Pride