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TranscriptomicsSingle-cell transcriptome analyses reveal signals to activate dormant neural stem cells.
Through single cell transcriptome analysis, we uncovered molecular signatures of CD133+/GFAP- ependymal (E) cells, CD133+/GFAP+ neural stem (B) cells, Dlx2+ neuroblasts (A cells), and Sox10+ oligodendrocyte progenitors (O cells) in the adult mouse forebrain neurogenic zone. prominent hub genes of th...
ORGANISM(S): Mus musculus 
2015-05-21 | E-GEOD-61288 | biostudies-arrayexpress
TranscriptomicsExpression data from endthelial cells in ductus arteriosus and aorta in rat fetuses or neonates
Endothelial cells (Ecs) lining the blood vessels have been known to have a variety of functions and play a central role in homeostasis of the circulatory system. Since ductus arteriosus (DA) has unique characteristics comparing other vessels, we hypothesized that ECs were the primary target to inves...
ORGANISM(S): Rattus norvegicus 
2013-10-01 | E-GEOD-40500 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of human MOLT4 cell lines before and after inhibition of gamma secretase to investigate NOTCH signaling in T-cell acute lymphoblastic leukemia cell lines
In T-cell acute lymphoblastic leukemia (T-ALL) NOTCH 1 receptors are frequently mutated. This leads to aberrantly high Notch signaling, but how this translates into deregulated cell cycle control and the transformed cell type is poorly understood. In this report, we analyze downstream responses resu...
ORGANISM(S): Homo sapiens 
2008-06-14 | E-GEOD-6495 | biostudies-arrayexpress
TranscriptomicsMicroarray using CD31+/CD41-/CD45- cells from E9.5 mouse heart tube, caudal half and yolk sac
Hematopoietic cells arise from spatiotemporally restricted domains in the developing embryo. Although studies of non-mammalian animal and in vitro embryonic stem cell models suggest a close relationship among cardiac, endocardial, and hematopoietic lineages, it remains unknown whether the mammalian ...
ORGANISM(S): Mus musculus 
2013-08-17 | E-GEOD-40260 | biostudies-arrayexpress
UnknownSilver lining to a climate crisis in multiple prospects for alleviating crop waterlogging under future climates.
Not available
S-EPMC9918449 | biostudies-literature
UnknownStructural and functional basis of low-affinity SAM/SAH-binding in the conserved MTase of the multi-segmented Alongshan virus distantly related to canonical unsegmented flaviviruses.
Not available
S-EPMC10575543 | biostudies-literature
UnknownThe Silver Lining of COVID-19: Estimation of Short-Term Health Impacts Due to Lockdown in the Yangtze River Delta Region, China.
Not available
S-EPMC7361223 | biostudies-literature
UnknownFire behaviors along timber linings affixed to tunnel walls in mines.
Not available
S-EPMC8639102 | biostudies-literature
UnknownExpression and functional pathway analysis of nuclear receptor NR2F2 in ovarian cancer.
Not available
S-EPMC3701283 | biostudies-literature
TranscriptomicsMicroRNA expression profiling in GC-2 cells following 50 Hz ELF-EMF
Aberrant miRNA expression has been related to the development of human germ cell tumors, but little is known about effect of ELF-EMFs on miRNA expression. ELF-EMFs may epigenetically modify cells, which may account for the adverse effects of ELF-EMFs on the male reproductive system. To identify miRN...
ORGANISM(S): Mus musculus 
2016-07-01 | E-GEOD-71147 | biostudies-arrayexpress
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