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MetabolomicsStage-specific roles of microbial dysbiosis and metabolic disorders in rheumatoid arthritis

OBJECTIVE: Rheumatoid arthritis (RA) is a progressive disease including four stages, where gut microbiome is associated with pathogenesis. We aimed to investigate stage-specific roles of microbial dysbiosis and metabolic disorders in RA.

METHODS: We investi...

2023-01-31 | MTBLS5297 | MetaboLights
UnknownTranscriptome Sequencing and Differential Analysis of Testes of 1-Year-Old and 3-Year-Old Kazakh Horses.
Not available
S-EPMC12784889 | biostudies-literature
TranscriptomicsGenome-wide transcriptome analysis of two maize inbred lines under drought stress during the seedling stage
To understand the transcriptome changes during drought tolerance in maize, the drought-tolerant line Han21 and drought-sensitive line Ye478, which show substantial differences in drought tolerance at the seedling stage, were selected for this study. Using the GeneChip Maize Genome Arrays, we applied...
ORGANISM(S): Zea mays 
2010-06-16 | E-GEOD-16567 | biostudies-arrayexpress
ProteomicsArtificial warming affects sugar signals and flavonoid accumulation to improve female willows growth faster than males
Warming posed a significant effect to plant growth. Dioecious species were especially vulnerable to warming climate given that they often exhibited a series of gender- specific physiological and morphological responses.Here, we conducted a controlled growth chamber experiments by using a female-bias...
ORGANISM(S): Salix Paraplesia 
2023-06-24 | PXD043259 |
ProteomicsProtein expression of Rhodopseudomonas palustris CGA009 during anaerobic nitrogen fixation or non nitrogen fixation
Rhodopseudomonas palustris CGA009 grown anaerobic in photosynthetic medium (PM) or Nitrogen-fixing medium (NFM)
ORGANISM(S): Rhodopseudomonas Palustris Cga009 
2023-06-01 | PXD042610 |
ProteomicsThe eWAT ubiquitinome of wild type mice and Mdm2 adipocyte-specific knock-in mice fed high-fat diet
The epididymal adipose tissue (eWAT) samples from wild type mice fed high-fat diet for 12 weeks (H_WT_E) and Mdm2 adipocyte-specific knock-in mice fed high-fat diet for 12 weeks (H_KI_E) were mixed separately, and subjected to ubiquitinome study by Label-free quantification and ubiquitination modifi...
ORGANISM(S): Mus Musculus 
2022-05-26 | PXD034127 |
ProteomicsRNA-Pull down and MS for Snhg3
To screen Snhg3-binding proteins using-RNA Pull down and MS
ORGANISM(S): Mus Musculus 
2023-01-17 | PXD039526 |
ProteomicsAmelioration of nonalcoholic fatty liver disease by inhibiting the deubiquitylating enzyme RPN11
Nonalcoholic fatty liver disease (NAFLD) including its more severe manifestation, nonalcoholic steatohepatitis (NASH), is a global public health challenge. Here, we reveal a role for the deubiquitinating enzyme RPN11 in the development of NAFLD and NASH. Ablation of hepatic RPN11 markedly protected ...
ORGANISM(S): Homo Sapiens Mus Musculus 
2024-06-15 | PXD053163 |
ProteomicsSi-pgc-1 α LNP prevents bladder cancer metastasis by inhibiting mitochondrial biogenesis and energy metabolism in cancer cells
This study aims to explore the effect of PGC-1 α siRNA delivered by liposomal nanoparticles on cancer cells through transcriptome, proteome and metabolome technologies, so as to reveal its regulatory effect on cancer cell reprogramming and energy metabolism, so as to provide clues for the molecular ...
ORGANISM(S): Mus Musculus 
2025-03-22 | PXD062155 |
ProteomicsTargeting PGC-1α in Bladder Cancer: Unraveling Energy Metabolism Reprogramming for Therapeutic Intervention
Metastatic bladder cancer is a malignant tumor with high metastatic potential. The etiology and molecular mechanism are still not fully understood. This study aimed to investigate the effect of PGC-1 α siRNA delivered by liposomal nanoparticles on bladder cancer cells, in order to reveal its mechani...
ORGANISM(S): Mus Musculus 
2025-03-22 | PXD062153 |
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