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Triple negative breast cancer (TNBC) is a heterogeneous and clinically aggressive disease for which there is no targeted therapy. Here we report the preferential and high sensitivity of TNBCs to BET bromodomain inhibitors such as JQ1 manifested by cell cycle arrest in early G1, apoptosis, and induct...
ORGANISM(S): Homo sapiens 

This project aims to conduct genome-wide association studies (GWAS) in two anatomically different upper gastrointestinal (UGI) cancer sites in two populations with distinctly different disease rates and genetic profiles. One population has very high rates for both esophageal squamous cel...

The proteomics analysis of total proteins extracted from the cerebral ischemic penumbra tissues of different groups three days after MCAO
ORGANISM(S): Mus Musculus 
2023-06-07 | PXD042777 |
Coimmunoprecipitation, detect binding protein of HMGB1 in primary microglials in control and LPS group
ORGANISM(S): Mus Musculus 
2023-06-07 | PXD042778 |
This SuperSeries is composed of the SubSeries listed below. Refer to individual Series
ORGANISM(S): Homo sapiens 
To assess the role of POLA in relation to ovule development, embryogenesis and endosperm development, we analyzed gene expression profiles by using microarray. Compared to the wild-type plants, several groups of transcription factors in the pola mutant plants and POLA RNAi lines showed up- or down-r...
ORGANISM(S): Oryza sativa Japonica Group 
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