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MetabolomicsEffects of Yulin Tong Bu formula on modulating gut microbiota and fecal metabolite interactions in mice with polycystic ovary syndrome

BACKGROUND: Polycystic ovarian syndrome (PCOS) is a common endocrine disorder characterized by hyperandrogenism, ovarian dysfunction and polycystic ovarian morphology. Gut microbiota dysbiosis and metabolite are associated with PCOS clinical parameters. Yulin Tong Bu formula (YLT...

2023-02-02 | MTBLS6736 | MetaboLights
MetabolomicsMg2+ in drinking water exacerbates Salmonella Typhimurium T6SS-mediated intestinal bacterial competition through affecting metabolic reprogramming

By establishing a model of enteritis in mice infected with Salmonella Typhimurium, this study investigates the effects of ion concentration in drinking water on intestinal metabolites and microbiota structure in mice, as well as its influence on pathogen susceptibility and the host-patho...

2025-12-30 | MTBLS12690 | MetaboLights
UnknownIFN-γ Driven Hepatic Injury Exacerbates Mortality in NK/T-Cell Lymphoma-Associated Hemophagocytic Lymphohistiocytosis.
Not available
S-EPMC12906978 | biostudies-literature
ProteomicsLong noncoding RNA HITT coordinates with RGS2 to inhibit PD-L1 translation in T cell immunity-proteome
Long noncoding RNA HITT coordinates with RGS2 to inhibit PD-L1 translation in T cell immunity
ORGANISM(S): Homo Sapiens 
2022-12-28 | PXD039107 |
UnknownComprehensive analysis of T-cell regulatory factors and tumor immune microenvironment in stomach adenocarcinoma.
Not available
S-EPMC11077837 | biostudies-literature
UnknownImmune Escape-Related Gene NXT1 as a Potential Prognostic and Therapeutic Target in Hepatocellular Carcinoma.
Not available
S-EPMC12824892 | biostudies-literature
ProteomicsTMT-Based Quantitative Proteomic Analysis Reveals the Crucial Biological Pathways Involved in Brain Injury Induced by Chest Exposure to Shock Waves
Long term chest blast exposure can lead to mental disorders, brain inflammation and oxidative stress in soldiers. However, the underlying mechanism of brain injury caused indirectly by chest blast remains unclear. It is urgent to find more potential biomarkers to reveal the deeper pathogenesis of th...
ORGANISM(S): Mus musculus (Mouse) 
2021-12-30 | PXD025204 | Pride
Chest blast  brain injury  tandem mass spectrometry quantitative proteomics  inflammation  signaling pathways 
UnknownAsparaginase enhances CAR-T cell antitumor immunity by asparagine metabolic reprogramming and central memory induction in ALL.
Not available
S-EPMC12628164 | biostudies-literature
ProteomicsTMT-Based Quantitative Proteomic Analysis Reveals the Crucial Biological Pathways Involved in Brain Injury Induced by Chest Exposure to Shock Waves
Long term chest blast exposure can lead to mental disorders, brain inflammation and oxidative stress in soldiers. However, the underlying mechanism of brain injury caused indirectly by chest blast remains unclear. It is urgent to find additional reliable biomarkers to reveal the intimate details of ...
ORGANISM(S): Rattus norvegicus (Rat) 
2022-02-17 | PXD026015 | Pride
Chest blast  brain injury  tandem mass spectrometry quantitative proteomics  inflammation  signaling pathways 
UnknownSpatial and Single-Cell Transcriptomics Reveal a Cancer-Associated Fibroblast Subset in HNSCC That Restricts Infiltration and Antitumor Activity of CD8+ T Cells.
Not available
S-EPMC10790129 | biostudies-literature
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