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UnknownIn vitro and in vivo analyses on anti-NSCLC activity of apatinib: rediscovery of a new drug target V600E mutation.
Not available
S-EPMC9909954 | biostudies-literature
UnknownIdentification of two major QTLs for pod shell thickness in peanut (Arachis hypogaea L.) using BSA-seq analysis.
Not available
S-EPMC10790476 | biostudies-literature
TranscriptomicsGene expression signatures and pathway analysis of esophageal squamous cell carcinoma
We identified a number of deregulated genes through transcriptome analysis on esophageal squamous cell carcinoma (ESCC) and adjacent normal tissues. Our pathway enrichment analysis suggested that deregulated genes were strongly enriched in multiple functionally linked pathways known to be important ...
ORGANISM(S): Homo sapiens 
2016-07-24 | E-GEOD-77531 | biostudies-arrayexpress
GenomicsLINE-1 DNA methylation levels in Midnolin KO and Midnolin overexpressing mouse embryonic stem cells
targeted associated bisulfite sequencing (TaBA-seq) on LINE1 elements in Midnolin (Midn) KO ESCs, and wild-type (wt) ESCs harboring a doxycycline-inducible Midnolin transgene in which Midnolin overexpression was induced for 3 days
ORGANISM(S): Mus musculus 
2026-03-01 | E-MTAB-15573 | biostudies-arrayexpress
MetabolomicsStudy on the Effect of Bee Venom and Its Main Component melittin In Delaying Skin Aging in Mice
Bee venom (BV) and its main compound melittin (MLT) have antioxidant, anti-inflammatory, and anti-aging activities; however, very little research has been conducted on their effects on skin aging. In this study, a mouse skin aging model induced by D-galactose (D-gal) was constructed via subcutaneous...
2025-05-12 | MTBLS11975 | MetaboLights
TranscriptomicsIdentification of inflammation-related microRNAs deregulated in the plasma from intracerebral hemorrhage patients
We tested the hypothesis that circulating microRNAs (miRNAs) present in plasma might display a specific signature in patients with intracerebral hemorrhage (ICH). Global miRNA profiles were determined with the Agilent Human miRNA Microarray platform, 027233. ICH patients display a characteristic inf...
ORGANISM(S): Homo sapiens 
2013-01-19 | E-GEOD-43618 | biostudies-arrayexpress
ProteomicsComprehensive kinomic study via a chemical proteomic approach reveals dynamic kinome reprogramming in hepatocellular carcinoma tissues
To identify kinases of potential therapeutic interest in HCC, a quantitative kinomic study of tumour and adjacent non-tumour liver tissues was performed using a chemical proteomic approach.
ORGANISM(S): Homo Sapiens 
2021-01-26 | PXD023806 |
ProteomicsCopper exposure aggravates motor phenotype via inhibiting mitophagy in SOD1G93A transgenic mice
Background Amyotrophic lateral sclerosis (ALS) is an age-dependent and incurable neurodegenerative disease. It is pathologically characterized by selective degeneration of motor neurons resulting in a catastrophic loss of motor function. Previous studies showed that excess copper (Cu) might have a r...
ORGANISM(S): Mus Musculus 
2023-01-29 | PXD039728 |
ProteomicsMass spectrometry-based protein interactome and phosphoproteomics data upon NRDE2 overexpression
The HEK293T cells transiently expressing Flag-tagged empty vector or Flag-NRDE2-WT were lysed in NETN buffer (10 mM Tris-HCl [pH 8.0], 100 mM NaCl, 1 mM EDTA, and 0.5% NP-40) and immunoprecipitated with anti-Flag M2 agarose (M8823; Sigma-Aldrich, MO, USA). After washing four times with the high stri...
ORGANISM(S): Homo Sapiens 
2024-03-31 | PXD051117 |
Genomicsena-DATASET-GoT2D/T2D-GENES-08-07-2016-21:22:44:693-1130 - samples
The T2D-GENES/GoT2D 13K exome sequencing study includes ~13,000 samples, half T2D cases and half T2D controls, from five ancestries (~5K Europeans, ~2K each of African-American, East-Asian, South-Asian, and Hispanic). Samples underwent deep exome sequencing, with SNVs and INDEls called according to ...
EGAD00001002246 | EGA
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