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TranscriptomicsTranscription profiling of human acne lesion vs. normal skin from acne and non acne patients
The pathogenesis of acne has been linked to multiple factors such as increased sebum production, inflammation, follicular hyperkeratinization, and the action of Propionibacterium acnes within the follicle. In an attempt to understand the specific genes involved in inflammatory acne, we performed gen...
ORGANISM(S): Homo sapiens 
2008-06-14 | E-GEOD-6475 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of human sebocytes (SEB-1) treated with 13-cis retinoic acid treatment
The pathogenesis of acne has been linked to multiple factors such as increased sebum production, inflammation, follicular hyperkeratinization, and the action of Propionibacterium acnes within the follicle. 13-cis Retinoic Acid (13-cis RA, isotretinoin) is the most potent agent in acne treatment. Su...
ORGANISM(S): Homo sapiens 
2008-04-06 | E-GEOD-10432 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of human immortalized sebocytes (SEB-1) treated with 13-cis retinoic acid to gain insights into its sebocyte-specific mechanism of action
This SuperSeries is composed of the following subset Series:; GSE10432: 13-cis retinoic acid treatment of human sebocytes (SEB-1); GSE10433: Human Skin: Before and 1 week after Isotretinoin Treatment; The pathogenesis of acne has been linked to multiple factors such as increased sebum production, in...
ORGANISM(S): Homo sapiens 
2008-04-06 | E-GEOD-10434 | biostudies-arrayexpress
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