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Unknown2-((1H-indol-3-yl)thio)-N-phenyl-acetamides: SARS-CoV-2 RNA-dependent RNA polymerase inhibitors.
Not available
S-EPMC8600920 | biostudies-literature
GenomicsGenome wide association study of leprosy in Chinese population

Leprosy is a chronic infectious disease caused by Mycobacterium leprae (M. leprae). Due to M. leprae's narrow host range and an inability to be cultured in vitro, the biological investigation of this disease has been difficult. Host genetic factors have been ...

phs000217.v1.p1 | EGA
UnknownJoining Illumina paired-end reads for classifying phylogenetic marker sequences.
Not available
S-EPMC7071698 | biostudies-literature
TranscriptomicsAmiloride modulates alternative splicing in leukemic cells and re-sensitizes Bcr-AblT315I mutant cells to imatinib
We have discovered that amiloride can produce a genome-wide effect on alternative splicing of various RNA transcripts, most importantly including those of the apoptotic factors, in K562 leukemic cells. Target was prepared from 4 biological replicates of 0.5 mM amiloride-treatment for 24hr and 3 cont...
ORGANISM(S): Homo sapiens 
2012-09-17 | E-GEOD-24976 | biostudies-arrayexpress
UnknownRNA-binding protein SAMD4A targets FGF2 to regulate cardiomyocyte lineage specification from human embryonic stem cells.
Not available
S-EPMC11921648 | biostudies-literature
TranscriptomicsTranscription profiling of mouse brains of E14.5, E16.5 and E18.5 Top2b+/+ and top2b-/- embryos to study the role of DNA Topoisomerase IIbeta in gene expression
Mice lacking topoisomerase IIbeta (Top IIbeta) are known to exhibit a perinatal death phenotype. In the current study, transcription profiles of the brains of wild type and top2beta knockout mouse embryos were generated. Surprisingly, only a small number (1-4%) of genes were affected in top2beta kno...
ORGANISM(S): Mus musculus 
2007-11-22 | E-GEOD-5458 | biostudies-arrayexpress
UnknownAssociations of ACE I/D and AGTR1 rs5182 polymorphisms with diabetes and their effects on lipids in an elderly Chinese population.
Not available
S-EPMC11290002 | biostudies-literature
UnknownLongitudinal Undetectable Molecular Residual Disease Defines Potentially Cured Population in Localized Non-Small Cell Lung Cancer.
Not available
S-EPMC9394392 | biostudies-literature
UnknownCirculating Tumor DNA-Guided De-Escalation Targeted Therapy for Advanced Non-Small Cell Lung Cancer: A Nonrandomized Controlled Trial.
Not available
S-EPMC12312504 | biostudies-literature
MetabolomicsPlot diversity differentially affects the chemical composition of leaves, roots and root exudates in four subtropical tree species

Plants produce thousands of compounds, collectively called the metabolome, which mediate interactions with other organisms. The metabolome of an individual plant may change according to the number and nature of these interactions. We tested the hypothesis that tree diversity level affects the met...

2021-08-09 | MTBLS1968 | MetaboLights
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