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UnknownCombination of Youhua Kuijie Prescription and sulfasalazine can alleviate experimental colitis via IL-6/JAK2/STAT3 pathway.
Not available
S-EPMC11420560 | biostudies-literature
ProteomicsHuh-7 exosomes and HBV
Hepatitis B virus (HBV) infection could cause hepatitis, liver cirrhosis and hepatocellular carcinoma. HBV-mediated pathogenesis is only partially understood, but X protein (HBx) reportedly possesses oncogenic potential. Exosomes are small membrane vesicles with diverse functions released by various...
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
2017-03-29 | MSV000080794 | MassIVE
ProteomicsHuh-7 exosomes and HBV - Quantitative Proteomic Analysis of Exosome Protein Content Changes Induced by Hepatitis B Virus in Huh-7 Cells Using SILAC Labeling and LC-MS/MS
Hepatitis B virus (HBV) infection could cause hepatitis, liver cirrhosis and hepatocellular carcinoma. HBV-mediated pathogenesis is only partially understood, but X protein (HBx) reportedly possesses oncogenic potential. Exosomes are small membrane vesicles with diverse functions released by various...
ORGANISM(S): Homo sapiens (Human) 
2014-10-09 | PXD001339 | Pride
Hbx Exosome Hepatitis b virus 
ProteomicsTNFAIP8-containing exosomes from injured tubular epithelial cells inhibit fibroblast apoptosis in fibrotic kidney
Tubule-derived exosomes play an essential role in mediating population of fibroblasts and renal fibrogenesis through shuttling TNFAIP8 to block p53 pathway
ORGANISM(S): Homo Sapiens 
2022-06-16 | PXD034545 |
ProteomicsProteomic profiling of the kidney tissue scaffold from normal and fibrotic kidneys
The proteomic profiling of the kidney tissue scaffold derived from normal and fibrotic kidneys was carried out by an unbiased LC-MS/MS approach.
ORGANISM(S): Mus <genus> 
2023-03-15 | PXD034281 |
ProteomicsFibroblast-derived Smoothened governs prognosis of acute kidney injury
Although the tubule is the epicenter of damage, kidney fibroblast is increasingly appreciated in governing the prognosis of acute kidney injury (AKI). Smoothened (Smo), a heptahelical transmembrane protein, carries a hedgehog signal to mediate the communications between kidney fibroblasts and tubula...
ORGANISM(S): Mus Musculus (ncbitaxon:10090) 
2021-12-23 | MSV000088609 | MassIVE
ProteomicsCircular RNA circBNC2 regulates epithelial cell G2-M arrest to prevent fibrotic maladaptive repair
Epithelial cells arrested in G2/M phase of the cell cycle after injury is a key checkpoint for determining the wound-healing to either normal cell proliferation or fibrosis. The mechanism that regulates the fibrogenic response after injury is not well understood. Here, we identified a kidney- and li...
ORGANISM(S): Homo Sapiens 
PXD033284 |
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