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Yersinia pestis is a lethal pathogen responsible for millions of human deaths in three worldwide pandemics.The global acetylome analyses of Y. pestis grown under conditions mimicking two typical niches, i.e., the mammalian host (Mh) and the flea vector (Fv), were performed.
ORGANISM(S): Yersinia Pestis Biovar Microtus Str. 91001 
2023-07-06 | PXD038124 |
SIRT3 is a NAD+-dependent mitochondrial protein deacetylase participating in the regulation of central metabolism and mitochondrial proteostasis. SIRT3 is downregulated in clear cell renal cell carcinoma (ccRCC), a main type of renal cancers, but the function of SIRT3 in tumorigenesis and developmen...
ORGANISM(S): Homo sapiens (Human) 
2018-08-14 | PXD009110 | Pride
Proteomic data showed the adaptation mechanism of Ulva prolifera to 12-hour high light.
ORGANISM(S): Ulva Prolifera 
2022-05-11 | PXD033819 |
Circadian clocks generate endogenous rhythms in most organisms from cyanobacteria to humans and facilitate entrainment to environmental diurnal cycles, thus conferring a fitness advantage. Both transcriptional and posttranslational mechanisms are prominent in the basic network architecture of circad...
ORGANISM(S): Arabidopsis thaliana 
Whole-genome transcriptional profiles of rice cell types, isolated by laser-capture microdissection. The first comprehensive multi-organ cell type transcriptome atlas from a plant, with 40 distinct cell types from several developmental stages of seeds, shoots and roots, reveals cell-specific promote...
ORGANISM(S): Oryza sativa 
Translation initiation factor eIF5A facilitates protein synthesis and impacts diverse biological processes, yet its role in transcriptional regulation is poorly understood. Here we find eIF5A highly expressed in diverse spermatogenic cell types. Conditional knockout of Eif5a (SKO) causes complete in...
ORGANISM(S): Mus Musculus 
Glioblastoma (GBM) is the most common and aggressive malignant brain tumor with poor prognosis. Temozolomide (TMZ) is the standard chemotherapy for glioblastoma treatment, but TMZ resistance significantly compromises its efficacy. In the present study, we generated a TMZ-resistant cell line and iden...
ORGANISM(S): Homo Sapiens 
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