Hyperglycemia accelerates calcification of atherosclerotic plaques in diabetic patients, and the prolonged accumulation of advanced glycation end products (AGEs) induced by hyperglycemia may be closely related to the pathogenesis of aortic calcification. However, the mechanisms underlying this assoc...
O-glycosylation is a critical post-translational modification (PTM) regulating protein function, yet its role in plant transcription factors remains poorly understood.
We isolated PDGFRβ+ mural cells from tumor-adjacent normal human brain, lung, and kidney tissues. After lysis, we used LC-MS to profile differentially expressed proteins across these three cell types.