Sort   by:  
 Page size 
MetabolomicsTranscriptomics and Metabolomics Reveal Alterations in Xenobiotic Metabolism and Appearance of Steroidal Alkaloid Metabolites in Mouse Livers after Tomato Consumption

SCOPE: Tomato consumption is associated with many health benefits including lowered risk for developing certain cancers. It is hypothesized that tomato phytochemicals are transported to the liver and other tissues where they alter gene expression in ways that lead to favorable he...

2023-06-13 | MTBLS6715 | MetaboLights
MetabolomicsSpatially resolved characterization of tissue metabolic compartments in fasted and high-fat diet livers
Not available
ORGANISM(S): Mus musculus 
ST002219 | MetabolomicsWorkbench
TranscriptomicsDiet-induced chromatin remodeling in mice livers
The tissue-specific packaging of the genome into the nucleus through chromatin is fundamentally involved in gene regulation, and aberrant modifications to chromatin are a hallmark of many diseases. We show here that a high fat (HF) diet leads to substantial chromatin remodeling in the livers of C57B...
ORGANISM(S): Mus musculus 
2014-07-17 | E-GEOD-55581 | biostudies-arrayexpress
TranscriptomicsExpression data of hepatocytes isolated from chimeric mouse livers repopulated with human hepatocytes and from normal human livers
We generated chimeric mice with livers that were predominantly repopulated with human hepatocytes. Hepatocytes were isolated from the chimeric mouse livers and their gene expressions were compared with hepatocytes isolated from normal human livers . Cluster and principal components analyses showed t...
ORGANISM(S): Mus musculus 
2012-11-27 | E-GEOD-33846 | biostudies-arrayexpress
TranscriptomicsThe gene expression profiles of WT and NML-KO livers
To examine whether energy starvation caused by the increase in rRNA transcription affects liver metabolism, we compared the gene expression profiles of WT and NML-KO livers using Affymetrix microarray technology. We analyzed 5 livers of WT mice and 5 livers of NML-KO mice.
ORGANISM(S): Mus musculus 
2013-06-22 | E-GEOD-48191 | biostudies-arrayexpress
ProteomicsQuantitative proteomics of rat livers shows that unrestricted feeding and re-feeding after food restriction are stressful for cellular proteostasis
We used quantitative MS-based proteomic analysis of whole rat livers to study the molecular events associated with a food restriction regimen as compared with ad libitum food and animals re-fed after a restriction time.
ORGANISM(S): Rattus norvegicus (Rat) 
2016-12-23 | PXD004068 | Pride
Food restriction Liver Rat Food intake Label-free 
TranscriptomicsComparison of gene expression profiles of wildtype and two lines of Nrf2 knockout rat livers with or without CDDO-Im treatment
Whole livers were collected from rats treated with or without CDDO-Im. Total RNA was purified using Sepazol-RNA I Super G. Gene expression was measured in livers.
ORGANISM(S): Rattus norvegicus 
2016-08-10 | E-GEOD-77377 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of clofibrate treated rat livers
5 day q.d. treatment by oral gavage of SD rats using 0, 200, 400 or 800 mg/kg/day of the peroxisome proliferator clofibrate. Livers were removed, RNA was isolated, and Cy3/Cy5 probes generated for 2-channel microarray experiments.
ORGANISM(S): Rattus norvegicus 
2004-01-14 | E-MEXP-3 | biostudies-arrayexpress
TranscriptomicsExpression data from livers of C57BL/6J mice fed a high-fat diet and coffee
The present study was conducted to evaluate the effects of the intake of three types of coffee (caffeinated, decaffeinated, and green unroasted coffee) on the livers of C57BL/6J mice fed a high-fat diet, and to extensively elucidate the physiological responses to coffee intake by analysing the f...
ORGANISM(S): Mus musculus 
2013-12-10 | E-GEOD-53131 | biostudies-arrayexpress
GenomicsTE-associated chromatin variation in mice livers
Chromatin accessibility is a hallmark of active regulatory function in the genome and variation of chromatin accessibility across individuals has been shown to contribute to complex traits and disease susceptibility. However, the mechanisms responsible for chromatin variation among different individ...
ORGANISM(S): Mus musculus 
2016-07-14 | E-GEOD-75770 | biostudies-arrayexpress
Sort   by:  
 Page size