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MetabolomicsCommon Metabolic Pathways Implicated in Resistance to Chemotherapy Point to a Key Mitochondrial Role in Breast Cancer
Cancer cells are known to reprogram their metabolism to adapt to adverse conditions dictated by tumor growth and microenvironment. A subtype of cancer cells with stem-like properties, known as cancer stem cells (CSC), is thought to be responsible for tumor recurrence. In this study, we demonstrated ...
2019-08-19 | MTBLS678 | MetaboLights
ProteomicsQUANTITATIVE PROTEOMIC ANALYSIS OF HUMAN CELL CULTURES USING TMT ISOBARIC TAG LABELLING AND NANOLC-ORBITRAP
Quantitative Proteomic analysis of 9 human cell culture cells from three different conditions. The analysis comprises the assessment of proteome changes due to different experimental conditions to find biological pathways involved.
ORGANISM(S): Homo sapiens (Human) 
2023-03-11 | PXD037118 | Pride
Human nlc-ms 
ProteomicsDefinition of key mechanisms of multidrug resistance of head and neck tumors to chemo- and radiotherapy treatments. Identification of new individualized antitumor drugs (Ref. GC16173720CARR)
Head and neck squamous cell carcinoma (HNSCC) is the sixth most commonly diagnosed cancer worldwide, with an incidence of about 600,000 new cases per year, accounting for 1-2% of all cancer deaths worldwide. Current treatment for head and neck cancer includes taxol (docetaxel), platinum compounds (e...
ORGANISM(S): Homo sapiens (Human) 
2020-11-12 | PXD020159 | Pride
Cancer stem cells Chemoresistance Hnscc 
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