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The aims of the study was to explore the tumor proteome of patients diagnosed with localized ccRCC and treated with surgery and the identification of altered pathways that could be the target of new treatments. A total of 165 FFPE tumor samples from patients diagnosed with ccRCC were analyzed using ...
ORGANISM(S): Homo sapiens (Human) 
2025-05-09 | PXD039258 | Pride
The development of clear cell renal cell carcinoma (ccRCC) is connected with disturbed glycolytic processes leading to the highly reactive dicarbonyls generation, resulting in protein modifications by advanced glycation end products (AGEs). Therefore, the present study aimed to analyze the level of ...
ORGANISM(S): Homo sapiens (Human) 
2026-02-09 | PXD059009 | Pride
The pituitary-tumor transforming gene (PTTG1) is a recently discovered oncogene implicated in the malignant progression of a number of neoplasms. It has been shown to drive both endocrine and non-endocrine malignancies, but has not yet been studied in the context of renal cell carcinoma. Here we sho...
ORGANISM(S): Homo sapiens 
Generation of a Comprehensive Epigenomic Atlas in Clear Cell Renal Cell Carcinoma Informs Kidney Cancer Progression and Heritability
Large-scale analysis of cell-cell communication reveals angiogenin-dependent tumor progression in clear cell renal cell carcinoma
MicroRNAs (miRNAs) are short single stranded RNAs that are associated with gene regulation at the transcriptional and translational level. Changes in their expression were found in a variety of human cancers. Because of the lack of corresponding data in clear renal cell carcinoma (ccRCC) we have per...
ORGANISM(S): Homo sapiens 
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