Sort   by:  
 Page size 
TranscriptomicsComparative transcriptomics of Mycobacterium bovis and Mycobacterium marinum
Related surrogate species are often used to study the molecular basis of pathogenicity of a pathogen on the basis of a shared set of biological features generally attributable to a shared core genome consisting of orthologous genes. An important and understudied aspect, however, is the extent to whi...
ORGANISM(S): Mycobacterium bovis 
2014-09-08 | E-GEOD-51881 | biostudies-arrayexpress
TranscriptomicsHigh-throughput sequencing of human macrophages infected with Mycobacterium abscessus Smooth and Rough variants
This SuperSeries is composed of the SubSeries listed below. Refer to individual Series
ORGANISM(S): Homo sapiens 
2015-09-09 | E-GEOD-72822 | biostudies-arrayexpress
TranscriptomicsRNA-seq profiling of theca and granulosa tissue of dominant follicle at 3 stages of follicular development in cows and heifers.
Cellular mechanisms that contribute to low estradiol concentrations produced by the preovulatory ovarian follicle in cattle with a compromised metabolic status (such as lactatino) are largely unknown. To gain insight into the main metabolic mechanisms affecting preovulatory follicle function RNAseq ...
ORGANISM(S): Bos taurus 
2012-06-15 | E-GEOD-34317 | biostudies-arrayexpress
TranscriptomicsHigh-throughput small RNA-sequencing of human macrophages infected with Mycobacterium abscessus Smooth and Rough variants
Mycobacterium abscessus is an emerging pathogen causing pulmonary infections in those with inflammatory lung disorders, such as Cystic Fibrosis (CF), and is associated with the highest fatality rate among rapidly growing mycobacteria (RGM). Phenotypically, MAB manifests as either a Smooth (MAB-S) or...
ORGANISM(S): Homo sapiens 
2015-09-09 | E-GEOD-72769 | biostudies-arrayexpress
TranscriptomicsHigh-throughput RNA-sequencing of human macrophages infected with Mycobacterium abscessus Smooth and Rough variants
Mycobacterium abscessus is an emerging pathogen causing pulmonary infections in those with inflammatory lung disorders, such as Cystic Fibrosis (CF), and is associated with the highest fatality rate among rapidly growing mycobacteria (RGM). Phenotypically, MAB manifests as either a Smooth (MAB-S) or...
ORGANISM(S): Homo sapiens 
2015-09-09 | E-GEOD-72821 | biostudies-arrayexpress
TranscriptomicsCharacterization of the equine skeletal muscle transcriptome identifies novel functional responses to exercise training
Digital gene expression profiling was used to characterize the assembly of genes expressed in equine skeletal muscle and to identify the subset of genes that were differentially expressed following a ten month period of exercise training. The study cohort comprised 7 thoroughbred racehorses from a s...
ORGANISM(S): Equus caballus 
2010-04-09 | E-GEOD-21269 | biostudies-arrayexpress
TranscriptomicsRNA sequencing of Mycobacterium abscessus under infection-relevant conditions
RNA sequencing (RNA-seq) of Mycobacterium abscessus in four infection-relevant culture conditions: hypoxic stress, artificial sputum medium, kanamycin-treated medium, and erythromycin-treated medium. Triplicate cultures of M. abscessus were grown in (1) Artificial Sputum media, (2) hypoxic condition...
ORGANISM(S): Mycobacterium abscessus 
2016-03-02 | E-GEOD-78787 | biostudies-arrayexpress
TranscriptomicsAn integrated approach combining RNA-seq, Ribo-seq and Proteomics identifies the coding potential of Mycobacterium abscessus
The objective of this study is to develop an integrated map for the M. abscessus ATCC19977 organism. Among the data types contributing to the development of this map are next-generation RNA-sequencing, differential RNA-sequencing, ribosome profiling, and mass spectrometry. The design of the study co...
ORGANISM(S): Mycobacterium abscessus ATCC 19977 
2016-03-30 | E-GEOD-72996 | biostudies-arrayexpress
GenomicStudy of Irish Amyotrophic Lateral Sclerosis (SIALS)

Amyotrophic lateral sclerosis (ALS) is a fatal neurodegenerative disease characterized by loss of motor neurons. Epidemiological studies indicate that 2-5% of cases are familial, usually with an autosomal dominant pattern of inheritance. For a portion of these, causative genes have been...

phs000127 | dbGaP
TranscriptomicsWhole-transcriptome, high-throughput RNA sequence analysis of the bovine macrophage response to MycobacteriumM-BM- bovis infection in vitro
Background: MycobacteriumM-BM- bovis, the causative agent of bovine tuberculosis, is an intracellular pathogen that can persist inside host macrophages during infection via a diverse range of mechanisms that subvert the host immune response. In the current study, we have analysed and compared the tr...
ORGANISM(S): Bos taurus 
2013-03-26 | E-GEOD-45439 | biostudies-arrayexpress
Sort   by:  
 Page size