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MetabolomicsUntargeted metabolomics of long-term drug intervention under standard diet in mice associated with lifespan

This study investigates urinary metabolic differences in young mice, aged mice, and aged mice supplemented with long-term drug intervention under standard diet. Untargeted metabolomics was performed using UHPLC-MS/MS in both positive (POS) and negative (NEG) ionization modes. The dataset provides...

2026-05-07 | MTBLS12889 | MetaboLights
ProteomicsDipsacus asperoides C. Y. Cheng et T. M. Ai, LC-MSMS
Pentacyclic triterpenes are a class of natural products that are present in Dipsacus asperoides with a long history of use. Pharmacological studies have shown that pentacyclic triterpenes have various biological activities. We have performed proteomic analysis in multiple tissues of this species to ...
ORGANISM(S): Dipsacus asperoides 
2023-02-09 | PXD038580 | Pride
Lc-msms Dipsacus asperoides c. y. cheng et t. m. ai 
TranscriptomicsDifferentially regulated genes in control and c-myc N-myc deficient LT-HSCs
Analysis of HSCs from control and c-myc N-myc deficient long-term hematopoietic stem cells. HSCs lacking both c-myc and N-myc display increased apoptosis rates. Data provide insight into the molecular changes occuring upon complete loss of Myc activity, clarifying the resulting apoptotic mechanism a...
ORGANISM(S): Mus musculus 
2009-02-20 | E-GEOD-12467 | biostudies-arrayexpress
TranscriptomicsTime-course gene expression profiles of a Saccharomyces cerevisiae wild type and long-lived sch9-delta mutant
The SCH9 null strain has smaller cell size, grows at a slower rate and survives three times longer than wide-type yeast. This study aims to dissect the mechanisms that lead to the yeast life span extension of sch9-delta. We measure gene expression profiles of the S. cerevisiae wild type and the lon...
ORGANISM(S): Saccharomyces cerevisiae 
2009-12-24 | E-GEOD-14227 | biostudies-arrayexpress
UnknownAn extended 36-week oral esomeprazole improved long-term recurrent peptic ulcer bleeding in patients at high risk of rebleeding.
Not available
S-EPMC9585769 | biostudies-literature
UnknownEffect of memantine on C-reactive protein and lipid profiles in bipolar disorder.
Not available
S-EPMC7241092 | biostudies-literature
UnknownA complex hepatitis B virus (X/C) recombinant is common in Long An county, Guangxi and may have originated in southern China.
Not available
S-EPMC3081081 | biostudies-literature
ProteomicsLong term effects of ethanol intake on the CYP450 enzyme system in the liver of AFLD rats
Alcoholic fatty liver disease (AFLD) is a liver disease closely related to long-term alcohol consumption. Although it is known that liver microsomal cytochrome P450 enzyme (CYP450) plays a crucial role in metabolizing alcohol and various exogenous compounds, the specific mechanism by which alcohol a...
ORGANISM(S): Mus Musculus 
2025-04-27 | PXD063375 |
TranscriptomicsDifferential gene expression profiling of MIHA cells transfected with C-terminal truncated HBx mutants
To compare the differentially expressed transcriptomes between MIHA cells transfected with empty vector control or different C-terminal truncated HBx mutants (14 or 35 amino acid carboxyl-terminal truncation - i.e. d14 and d35) mRNA profiles of MIHA cells stably overexpressing empty vector control o...
ORGANISM(S): Homo sapiens 
2016-08-02 | E-GEOD-71993 | biostudies-arrayexpress
UnknownTherapeutic potential of nanoceria pretreatment in preventing the development of urological chronic pelvic pain syndrome: Immunomodulation via reactive oxygen species scavenging and SerpinB2 downregulation.
Not available
S-EPMC9842028 | biostudies-literature
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