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TranscriptomicsTranscriptional profiling of E. coli after addition of peroxynitrite or hydrogen peroxide to aerobically growing cells
Peroxynitrite is formed in macrophages by the diffusion-limited reaction of superoxide and nitric oxide. This highly reactive species is capable of causing both oxidative and nitrosative stress in Escherichia coli. Previous studies have focused on the reactions of peroxynitrite with specific protein...
ORGANISM(S): Escherichia coli 
2010-05-24 | E-GEOD-19370 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of SET-2 deletion and wild type yeast on sense and anti-sense arrays
The presence of Set2-mediated methylation of H3K36 (K36me) correlates with transcription frequency throughout the yeast genome. K36me targets the Rpd3S complex to deacetylate transcribed regions and suppress cryptic transcription initiation at certain genes. Here, using a genome-wide approach, we r...
ORGANISM(S): Saccharomyces cerevisiae 
2009-03-03 | E-TABM-265 | biostudies-arrayexpress
TranscriptomicsDifferential Gene Expression of Soluble CD8+ T-cell mediated suppression of HIV replication in three older children
Goal: To compare the gene expression profiles from pediatric patients with each other, with those reported in adults and in those related to exosomes. Background: Suppression of human immunodeficiency virus (HIV) replication by CD8+ T-cells (CD8 suppression) contributes to survival in adults and chi...
ORGANISM(S): Homo sapiens 
2010-10-28 | E-GEOD-23183 | biostudies-arrayexpress
UnknownAdult-onset very-long-chain acyl-CoA dehydrogenase deficiency (VLCADD).
Not available
S-EPMC8006598 | biostudies-literature
MetabolomicsMetabolomics of Solanum lycopersicum infected by Phytophthora infestans leads to Late blight detection and reveals metabolic differences in infection times
Tomato crops suffer attacks of various pathogens that cause large production losses. Late blight caused by Phytophthora infestans is a devastating disease in tomatoes because of its difficultly to control. Here, we applied metabolomics based on liquid chromatography–mass spectrometry (LC-MS) and met...
2019-01-24 | MTBLS618 | MetaboLights
UnknownA Coaching-Based Leadership Program for Women Postdoctoral Fellows at the National Cancer Institute that Cultivates Self-confidence and Persistence in STEMM.
Not available
S-EPMC11461782 | biostudies-literature
MetabolomicsProtein-metabolite interactomics of carbohydrate metabolism reveal regulation of lactate dehydrogenase

Metabolic networks are interconnected and influence diverse cellular processes. The protein-metabolite interactions that mediate these networks are frequently low affinity and challenging to systematically discover. We developed mass spectrometry integrated with equilibrium dialysis for the disco...

2023-08-07 | MTBLS7237 | MetaboLights
TranscriptomicsReprogramming LCLs to iPSCs Results in Recovery of Donor-Specific Gene Expression Signature
Renewable in vitro cell cultures, such as lymphoblastoid cell lines (LCLs), have facilitated studies that contributed to our understanding of genetic influence on human traits. However, the degree to which cell lines faithfully maintain differences in donor-specific phenotypes is still debated. We h...
ORGANISM(S): Homo sapiens 
2014-12-17 | E-GEOD-64263 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of fission yeast wild type and zinc regulatory null mutant grown in low zinc growth conditions
Transcription profile of low zinc growth condition in zinc regulatory null mutant
ORGANISM(S): Schizosaccharomyces pombe 
2008-02-22 | E-TABM-427 | biostudies-arrayexpress
UnknownADR3, a next generation i-body to human RANKL, inhibits osteoclast formation and bone resorption.
Not available
S-EPMC9929471 | biostudies-literature
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