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GenomicsConserved Cis-Acting Range Extender Elements Mediate Long-Range Developmental Enhancer Activity in Mammals
Conserved Cis-Acting Range Extender Elements Mediate Long-Range Developmental Enhancer Activity in Mammals
PRJNA1019308 | ENA
UnknownAnalysis on long-range residue-residue communication using molecular dynamics.
Not available
S-EPMC4206573 | biostudies-literature
UnknownA chromatin insulator mediates transgene homing and very long-range enhancer-promoter communication.
Not available
S-EPMC2730365 | biostudies-literature
UnknownStructural identification of the pathway of long-range communication in an allosteric enzyme.
Not available
S-EPMC2538848 | biostudies-literature
UnknownLong-Range Signaling in MutS and MSH Homologs via Switching of Dynamic Communication Pathways.
Not available
S-EPMC5074593 | biostudies-literature
GenomicsA new model for long-range chromatin reorganisation linked to enhancer activation [ChIP-chip]
A new model for long-range chromatin reorganisation linked to enhancer activation [ChIP-chip]
PRJNA475629 | ENA
UnknownLong-Range Ruthenium-Amine Electronic Communication through the para-Oligophenylene Wire.
Not available
S-EPMC4561373 | biostudies-literature
TranscriptomicsConserved Cis-Acting Range Extender Elements Mediate Long-Range Developmental Enhancer Activity in Mammals
Long-range developmental enhancers can regulate cell-type specific target gene expression over distances that exceed hundreds of thousands of base pairs in mammals. Although higher-order chromatin organization provides support for such long-range enhancer—promoter interactions, the genetic factors t...
ORGANISM(S): Mus musculus 
2024-05-28 | GSE243635 | GEO
ProteomicsHierarchical antagonistic regulatory elements in the TRPV4 intrinsically disordered N-terminus modulate lipid binding and channel activity through transient long-range interactions
Intrinsically disordered regions (IDRs) are important for the functional regulation of membrane receptors. Among the TRP Vanilloid channels involved in thermo- and osmosensation, TRPV4 features the largest N-terminal IDR of ~150 residues. Here, we elucidate the structural ensemble of the TRPV4 IDR t...
ORGANISM(S): Gallus gallus (Chicken) 
2023-08-01 | PXD038153 | Pride
Trp channel Integrated structural biology Intrinsically disordered protein Long-range communication Pip2 binding 
OtherA new model for long-range chromatin reorganization linked to enhancer activation [5C]
The most prominent model for long-range enhancer regulation involves direct enhancer-promoter interaction by looping out the intervening chromatin. Using a synthetic biology approach, we have determined that a chromatin unfolding bteween Shh and its enhancers is regulated specifically by the Shh-Bra...
ORGANISM(S): Mus musculus 
2016-11-02 | GSE89388 | GEO
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