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MetabolomicsSearching for Drug Synergy Against Cancer Through Polyamine Metabolism Impairment: Insight Into the Metabolic Effect of Indomethacin on Lung Cancer Cells
Non-small cell lung cancer (NSCLC) is the most lethal and prevalent type of lung cancer. In almost all types of cancer, the levels of polyamines (putrescine, spermidine, and spermine) are increased, playing a pivotal role in tumor proliferation. Indomethacin, a non-steroidal anti-inflammatory drug, ...
2021-02-08 | MTBLS873 | MetaboLights
ProteomicsProteomics from centrosome-enriched fractions of Jurkat E6-1 human T cells, human embryonic kidney 293 cells, resting human T lymphoblasts and activated human T lymphoblasts
Centrosome-enriched fractions of Jurkat E6-1 human T cells (JK), human embryonic kidney (HEK) 293 cells, resting human T lymphoblasts (LT CTRL) and activated human T lymphoblasts (LT ACT), with one biological replicate for each condition, were analysed by label-free LC-MS/MS. For further details, re...
ORGANISM(S): Homo sapiens (Human) 
2025-12-18 | PXD063199 | Pride
Hek T lymphoblasts Jurkat Post-translational modifications Human Itraq Lc-ms/ms 
ProteomicsIdentification of spidroin proteins in the silk glands of Nephila clavipes spiders
Glands were frozen at -80 ºC immediately after being retrieved and stored under this condition until initiating the proteomics analysis protocol. Glands were washed with cold PBS and immersed in 120 l of homogenization buffer (50 mM Tris-HCl, pH 6.8, 10 mM DTT, 4% (w/v) SDS). Glands were boiled for ...
ORGANISM(S): Trichonephila clavipes 
2022-12-07 | PXD023141 | Pride
Spider silk  proteomics  liquid chromatography-tandem mass spectrometry  silk gut 
UnknownMolecular simulations of the interfacial properties in silk-hydroxyapatite composites.
Not available
S-EPMC9351605 | biostudies-literature
UnknownFamily Involvement in the Care of Nursing Home Residents With Dementia: A Scoping Review.
Not available
S-EPMC11992682 | biostudies-literature
UnknownA Novel Missense Variant Associated with A Splicing Defect in A Myopathic Form of PGK1 Deficiency in The Spanish Population.
Not available
S-EPMC6826351 | biostudies-literature
MetabolomicsEvaluation of sample preparation methods for NMR-based metabolomics of cow milk
The quality of milk metabolome analyzed by nuclear magnetic resonance (NMR) is greatly influenced by the way samples are prepared. Although this analytical method is increasingly used to study milk metabolites, a thorough examination of available sample preparation protocols for milk has not been re...
2019-06-13 | MTBLS623 | MetaboLights
UnknownThe TT genotype of the STAT4 rs7574865 polymorphism is associated with high disease activity and disability in patients with early arthritis.
Not available
S-EPMC3427144 | biostudies-literature
TranscriptomicsAnalysis of the genome content of Lactococcus garvieae by genomic interspecies microarray hybridization
Background: Lactococcus garvieae is a bacterial pathogen that affects different animal species and human. Despite the widespread distribution and emerging clinical significance of L. garvieae in both veterinary and human medicine, there is almost a complete lack of knowledge about the genetic conte...
ORGANISM(S): Lactococcus garvieae 
2010-03-23 | E-GEOD-19005 | biostudies-arrayexpress
UnknownMitochondrial genomes reveal the extinct Hippidion as an outgroup to all living equids.
Not available
S-EPMC4387498 | biostudies-literature
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