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ProteomicsSPY mediates O-fucose modification of hundreds of proteins and sugar-dependent growth in Arabidopsis_(Part 2: EtHCD)
The recent discovery of SPY-catalyzed protein O-fucosylation reveals a novel mechanism for regulating nucleocytoplasmic protein functions in plants. Genetic evidence indicates important roles of SPY in diverse developmental and physiological processes, however, the upstream signal controlling SPY ac...
ORGANISM(S): Arabidopsis thaliana (Mouse-ear cress) 
2023-05-10 | PXD038491 | Pride
O-fucosylation Proteomics Aal Mass spectrometry O-glycosylation 
ProteomicsSPY mediates O-fucose modification of hundreds of proteins and sugar-dependent growth in Arabidopsis_(Part 1: HCD)
The recent discovery of SPY-catalyzed protein O-fucosylation reveals a novel mechanism for regulating nucleocytoplasmic protein functions in plants. Genetic evidence indicates important roles of SPY in diverse developmental and physiological processes, however, the upstream signal controlling SPY ac...
ORGANISM(S): Arabidopsis thaliana (Mouse-ear cress) 
2023-05-10 | PXD038490 | Pride
O-fucosylation Aal Mass spectrometry O-glycosylation Proteomics. 
ProteomicsPost-translational modification of the transcription factor SPATULA by SECRET AGENT and SPINDLY promotes Arabidopsis style development.
O-linked-β-N-Acetylglucosamine (O-GlcNAc) and O-fucose are two sugar-based post-translational modifications (PTMs) whose mechanistic role in plant signalling and transcriptional regulation is still largely unknown. Here, we investigated how two O-glycosyltransferase enzymes of Arabidopsis thaliana, ...
ORGANISM(S): Arabidopsis thaliana (Mouse-ear cress) 
2024-01-22 | PXD037917 | Pride
Spy Spt O-glycosylation Gynoecium Sec 
ProteomicsPost-translational modification of the transcription factor SPATULA by SECRET AGENT and SPINDLY promotes Arabidopsis style development.
O-linked-β-N-Acetylglucosamine (O-GlcNAc) and O-fucose are two sugar-based post-translational modifications (PTMs) whose mechanistic role in plant signalling and transcriptional regulation is still largely unknown. Here, we investigated how two O-glycosyltransferase enzymes of Arabidopsis thaliana, ...
ORGANISM(S): Nicotiana tabacum (Common tobacco) 
2024-01-22 | PXD043957 | Pride
Spy Mass spectrometry Spt O-glycosylation Gynoecium Sec 
UnknownGenetic, metabolic and environmental factors involved in the development of liver cirrhosis in Mexico.
Not available
S-EPMC4631960 | biostudies-literature
UnknownUprolides N, O and P from the Panamanian Octocoral Eunicea succinea.
Not available
S-EPMC6273691 | biostudies-literature
UnknownGypsophila bermejoi G. Lopez: A possible case of speciation repressed by bioclimatic factors.
Not available
S-EPMC5770026 | biostudies-literature
MetabolomicsSearching for Drug Synergy Against Cancer Through Polyamine Metabolism Impairment: Insight Into the Metabolic Effect of Indomethacin on Lung Cancer Cells
Non-small cell lung cancer (NSCLC) is the most lethal and prevalent type of lung cancer. In almost all types of cancer, the levels of polyamines (putrescine, spermidine, and spermine) are increased, playing a pivotal role in tumor proliferation. Indomethacin, a non-steroidal anti-inflammatory drug, ...
2021-02-08 | MTBLS873 | MetaboLights
ProteomicsPost-translational modification of the transcription factor SPATULA by SECRET AGENT and SPINDLY promotes Arabidopsis style development.
O-linked-β-N-Acetylglucosamine (O-GlcNAc) and O-fucose are two sugar-based post-translational modifications (PTMs) whose mechanistic role in plant signalling and transcriptional regulation is still largely unknown. Here, we investigated how two O-glycosyltransferase enzymes of Arabidopsis thaliana, ...
ORGANISM(S): Arabidopsis thaliana (Mouse-ear cress) 
2024-01-22 | PXD043987 | Pride
Spy Mass spectrometry Spt O-glycosylation Gynoecium Sec 
ProteomicsPost-translational modification of the transcription factor SPATULA by SECRET AGENT and SPINDLY promotes Arabidopsis style development.
O-linked-β-N-Acetylglucosamine (O-GlcNAc) and O-fucose are two sugar-based post-translational modifications (PTMs) whose mechanistic role in plant signalling and transcriptional regulation is still largely unknown. Here, we investigated how two O-glycosyltransferase enzymes of Arabidopsis thaliana, ...
ORGANISM(S): Arabidopsis thaliana (Mouse-ear cress) 
2024-01-22 | PXD044034 | Pride
In vitro Proteomics Spy Mass spectrometry Spt O-glycosylation Gynoecium Sec 
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