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UnknownPooling and Analysis of Published in Vitro Data: A Proof of Concept Study for the Grouping of Nanoparticles.
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S-EPMC4661813 | biostudies-literature
TranscriptomicsMidbrain floor plate dopamine neurons from human ESCs efficiently engraft in murine and primate models of PD
Human pluripotent stem cells (hPSCs) are a promising source of cells for applications in regenerative medicine. Directed differentiation of hPSCs into specialized cells such as spinal motoneurons or midbrain dopamine (DA) neurons has been achieved. However the effective use of hPSCs for cell therap...
ORGANISM(S): Homo sapiens 
2011-11-07 | E-GEOD-32658 | biostudies-arrayexpress
ProteomicsMS-based phosphosite mapping in TKUL protein from Leishmania mexicana
Here we use MS to analyse the in-vitro autophosphorylation sites of the purified dual-functional protein, TKUL, from Leishmania mexicana.
ORGANISM(S): Leishmania mexicana MHOM/GT/2001/U1103 
2025-09-24 | PXD056904 | Pride
Tkul Phosphorylation Kinase Ubiquitin ligase Leishmania mexicana 
ProteomicsCalcium-triggered (de)ubiquitination events in synapses
Neuronal communication relies on neurotransmitter release from synaptic vesicles (SVs), whose dynamics are controlled by Ca2+-dependent pathways, as many thoroughly studied phosphorylation cascades. However, little is known about other post-translational modifications, as ubiquitination. To address ...
ORGANISM(S): Homo Sapiens Rattus Norvegicus 
PXD053470 | panorama
GenomicsNINDS-Genome-Wide Genotyping in Parkinson's Disease: First Stage Analysis and Public Release of Data

Epidemiological studies have estimated a cumulative prevalence of PD of greater than 1 per thousand. When prevalence is limited to senior populations, this proportion increases nearly 10-fold. The estimated genetic risk ratio for PD is approximately 1.7 (70% increased risk for PD if a sibling...

phs000089.v3.p2 | EGA
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