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TranscriptomicsTranscription profiling of human monocytes from pre-and post-menopausal women with high or low bone mineral density
Monocytes were isolated from 30 ml of whole blood from each of 19 women, 10 with high BMD and 9 with low BMD, using monocyte negative isolation kit from Dynal Biotech Inc. Total RNA was extracted from monocytes using Qiagen RNeasy Mini Kit. Targets were produced for each subject using standard Affym...
ORGANISM(S): Homo sapiens 
2007-08-25 | E-GEOD-2208 | biostudies-arrayexpress
ProteomicsLC-MSMS of postmenopausal with low BMD
Postmenopausal osteoporosis (PMOP) is a major global public health concern and older women are more susceptible to experiencing fragility fractures. Our study investigated the associations between circulating proteins with bone mineral density (BMD) in postmenopausal women with or without low BMD (o...
ORGANISM(S): Homo sapiens (Human) 
2020-04-27 | PXD017804 | Pride
Human Lc-msms Postmenopausal Low bmd Plasma 
TranscriptomicsTranscription profiling of human B-lymphocytes from postmenopausal female smokers with high or low bone mineral density
B cells produce important cytokines regulate bone metabolism. We comparison gene expression patterns of circulating B cells in blood from 20 postmenopausal female smokers with low or high bone mineral density (BMD): 10 low BMD vs. 10 high BMD. In total 17 differentially expressed genes were identifi...
ORGANISM(S): Homo sapiens 
2009-10-20 | E-GEOD-13850 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of human circulating B Lymphocytes from patients with high or low bone density
B cells produce important cytokines regulate bone metabolism. We comparison gene expression patterns of circulating B cells in blood from 20 postmenopausal females with low or high bone mineral density (BMD): 10 low BMD vs. 10 high BMD. In total 29 differentially expressed genes were identified incl...
ORGANISM(S): Homo sapiens 
2008-06-18 | E-GEOD-7429 | biostudies-arrayexpress
TranscriptomicsGene expression study of blood monocytes in pre- and postmenopausal females with low or high bone mineral density (HG-U133A)
Comparison of circulating monocytes from pre- and postmanopausal females with low or high bone mineral density (BMD). Circulating monocytes are progenitors of osteoclasts, and produce factors important to bone metabolism. Results provide insight into the role of monocytes in osteoporosis. We identif...
ORGANISM(S): Homo sapiens 
2016-06-01 | E-GEOD-56815 | biostudies-arrayexpress
TranscriptomicsGene expression study of blood monocytes in pre- and postmenopausal females with low or high bone mineral density (HuEx-1_0-st-v2)
Comparison of circulating monocytes from pre- and postmenopausal females with low or high bone mineral density (BMD). Circulating monocytes are progenitors of osteoclasts, and produce factors important to bone metabolism. Results provide insight into the role of monocytes in osteoporosis. We identif...
ORGANISM(S): Homo sapiens 
2016-06-01 | E-GEOD-56814 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of livers from female C57BL/6J and B6.C3H-6T mice to study differential gene expression in the two strains.
Several studies have shown that bone mineral density (BMD), a clinically measurable predictor of osteoporotic fracture, is the sum of genetic and environmental influences. In addition, serum IGF-1 levels have been correlated to both BMD and fracture risk. We previously identified a Quantitative Tr...
ORGANISM(S): Mus musculus 
2007-11-13 | E-GEOD-5959 | biostudies-arrayexpress
TranscriptomicsIdentification of known and novel long non-coding RNAs potentially responsible for the effects of BMD GWAS loci
Osteoporosis, characterized by low bone mineral density (BMD), is the most common complex disease affecting bone and constitutes a major societal health problem. Genome-wide association studies (GWASs) have identified over 1100 associations influencing BMD. It has been shown that perturbations to lo...
ORGANISM(S): Homo sapiens 
2021-11-04 | GSE186922 | GEO
UnknownDesign of a Computer Model for the Identification of Adolescent Swimmers at Risk of Low BMD.
Not available
S-EPMC9964481 | biostudies-literature
TranscriptomicsIdentification of known and novel long non-coding RNAs potentially responsible for the effects of BMD GWAS loci [hFOB RNA-seq]
Osteoporosis, characterized by low bone mineral density (BMD), is the most common complex disease affecting bone and constitutes a major societal health problem. Genome-wide association studies (GWASs) have identified over 1100 associations influencing BMD. It has been shown that perturbations to lo...
ORGANISM(S): Homo sapiens 
2025-04-04 | GSE293846 | GEO
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