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We used microarrays to assess differences in gene expression associated with single nucleotide polymorphisms occurred in three genes, PMA1, MDS3 and MKT1, as compared to a reference strain devoid of any mutations (Progenitor strain). Haploid yeast strains carrying no evolved alleles (progenitor - re...
ORGANISM(S): Saccharomyces cerevisiae 
Checkpoint kinase signaling in low dextrose growth conditions: SILAC phosphoproteome (IMAC-enriched peptides) - Light channel = dun1 deletion yeast grown in low dextrose minimal media. Heavy channel = rad53 deletion yeast grown in low dextrose minimal media.
ORGANISM(S): Saccharomyces cerevisiae (Baker's yeast) 
2020-07-28 | PXD020272 | Pride
BACKGROUND: Epidemiological evidence suggests a link between pesticide exposure and the development of metabolic diseases. However, most experimental studies have evaluated the metabolic effects of pesticides using individual molecules, often at non relevant doses or in combination with other r...
2019-05-28 | MTBLS596 | MetaboLights
Background: Survival and function of insulin-secreting pancreatic β-cells are markedly altered by changes in nutrient availability. In vitro, culture in 10 rather than 2mM glucose improves rodent β-cell survival and function whereas glucose concentrations above 10mM are deleterious. Aim-Method: T...
ORGANISM(S): Rattus norvegicus 
BACKGROUND: Epidemiological evidence suggests a link between pesticide exposure and the development of metabolic diseases. However, most experimental studies have evaluated the metabolic effects of pesticides using individual molecules, often at non-relevant doses or in combination with other r...
2018-05-01 | MTBLS602 | MetaboLights
We report the results of AcH3K9 ChIP-Seq on regenerating liver harvested 12 h after partial hepatectomy (PH) from mice treated with supplemental parenteral dextrose (to delay onset of PH-induced hypoglycemia) or vehicle (as control). Examination of the effect of delaying PH-induced hypoglycemia on h...
ORGANISM(S): Mus musculus 
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