Sort   by:  
 Page size 
GenomicsDifferential gene expression among HEK293T WT, LRPPRC-KO, LRPPRC-KO + WT, and LRPPRC-KO + Leigh Syndrome French Canadian type LRPPRC
Differential gene expression among HEK293T WT, LRPPRC-KO, LRPPRC-KO + WT, and LRPPRC-KO + Leigh Syndrome French Canadian type LRPPRC
PRJNA915041 | ENA
TranscriptomicsMitochondrial and nuclear genomic response to loss of LRPPRC expression
Rapid advances in genotyping and sequencing technology have dramatically accelerated the discovery of genes underlying human disease. Elucidating the function of such genes and understanding their role in pathogenesis, however, remains challenging. Here, we introduce a genomic strategy to function...
ORGANISM(S): Homo sapiens 
2010-03-23 | E-GEOD-20847 | biostudies-arrayexpress
ProteomicsProteomics profiling of Lrpprc knockout mice liver mitochondria following resolution by hybrid CN/BN PAGE
Mouse models of genetic mitochondrial diseases are generally used to understand specific molecular defects and their biochemical consequences, but rarely to map compensatory changes allowing survival. Here we took advantage of the extraordinary mitochondrial resilience of hepatic Lrpprc knockout mic...
ORGANISM(S): Mus musculus (Mouse) 
2021-09-09 | PXD021867 | Pride
Mitochondrial proteomics Mitochondrial electron transport chain Lrpprc Liver mitochondria Mitoribosomes Cardiolipin Genetic mitochondrial disease Mitochondrial lipidomics Mitochondrial supercomplexes Mitochondrial biogenesis Mitochondrial membrane lipids Mitochondrial translation Mitochondrial proteostasis 
TranscriptomicsDifferential gene expression among HEK293T WT, LRPPRC-KO, LRPPRC-KO + WT, and LRPPRC-KO + Leigh Syndrome French Canadian type LRPPRC
To investigate the role of LRPPRC and mutant LRPPRC on the stability of the mitochondrially encoded mRNA transcripts.
ORGANISM(S): Homo sapiens 
2023-12-22 | GSE221586 | GEO
GenomicsIdentification of the RNA-protein interactions of LRPPRC in A549
Identification of the RNA-protein interactions of LRPPRC in A549
PRJNA842725 | ENA
GenomicsDemethylzeylasteral inhibits oxidative phosphorylation complex biogenesis by targeting LRPPRC in lung cancer
Demethylzeylasteral inhibits oxidative phosphorylation complex biogenesis by targeting LRPPRC in lung cancer
PRJNA1170897 | ENA
ProteomicsComplexome Profiling of Lrpprc KO and WT mouse heart mitochondria
Complexome profiling was performed to address the changes in composition of ATP synthase assemblies upon knockout of Lrpprc in mouse heart.
ORGANISM(S): Mus musculus (Mouse) 
2026-05-20 | PXD075583 | Pride
UnknownLoss of LRPPRC causes ATP synthase deficiency.
Not available
S-EPMC3990160 | biostudies-literature
TranscriptomicsIdentification of the RNA-protein interactions of LRPPRC in A549
To map target transcripts bound with LRPPRC.
ORGANISM(S): Homo sapiens 
2023-05-10 | GSE204923 | GEO
TranscriptomicsDemethylzeylasteral inhibits oxidative phosphorylation complex biogenesis by targeting LRPPRC in lung cancer
Targeted inhibition of mitochondrial oxidative phosphorylation (OXPHOS) complex generation is an emerging and promising cancer treatment strategy, but limited targets and specific inhibitors have been reported. Leucine-rich pentatricopeptide repeat-containing protein (LRPPRC) is an atypical RNA-bind...
ORGANISM(S): Homo sapiens 
2024-10-09 | GSE279114 | GEO
Sort   by:  
 Page size