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UnknownStepwise maturation of the peptidyl transferase region of human mitoribosomes.
Not available
S-EPMC8208988 | biostudies-literature
ProteomicsEffects of SLIRP knockout in mouse mitochondria
Effects of SLIRP knockout in mouse mitochondria and mitoribosomes was studied using label-free quantitative proteomics
ORGANISM(S): Mus musculus (Mouse) 
2024-07-26 | PXD046268 | Pride
Mouse Heart Liver Mitochondria 
UnknownMrpL35, a mitospecific component of mitoribosomes, plays a key role in cytochrome c oxidase assembly.
Not available
S-EPMC5683760 | biostudies-literature
ProteomicsPPR proteins in Arabidopsis mitoribosomes
Investigation of the protein composition of mitoribosomal subunits in Arabidopsis thaliana by complexome profiling
ORGANISM(S): Arabidopsis thaliana (Mouse-ear cress) 
2019-04-30 | PXD011088 | Pride
Mitoribosomal subunits Ppr proteins Mitoribosomes Complexome profiling 
OtherTranslational activators align mitochondrial mRNAs at the small ribosomal subunit for translation initiation
Mitochondrial gene expression is essential for oxidative phosphorylation. Mitochondrial-encoded mRNAs are translated by dedicated mitochondrial ribosomes (mitoribosomes), whose regulation remains elusive. In the baker´s yeast Saccharomyces cerevisiae, nuclear-encoded mitochondrial translational acti...
ORGANISM(S): Saccharomyces cerevisiae 
2025-07-16 | GSE282943 | GEO
UnknownMessenger RNA delivery to mitoribosomes - hints from a bacterial toxin.
Not available
S-EPMC7891357 | biostudies-literature
OtherGTPBP8 is essential for mitoribosome formation in human mitochondria
Mitochondrial gene expression relies on mitoribosomes to translate mitochondrial mRNAs. The biogenesis of mitoribosomes is an intricate process involving multiple assembly factors. Among these factors, GTP-binding proteins (GTPBPs) play crucial roles. In bacterial systems, numerous GTPBPs are requir...
ORGANISM(S): Homo sapiens 
2024-06-19 | GSE256250 | GEO
TranscriptomicsGTPBP8 is essential for mitoribosome formation in human mitochondria
Mitochondrial gene expression relies on mitoribosomes to translate mitochondrial mRNAs. The biogenesis of mitoribosomes is an intricate process involving multiple assembly factors. Among these factors, GTP-binding proteins (GTPBPs) play crucial roles. In bacterial systems, numerous GTPBPs are requir...
ORGANISM(S): Homo sapiens 
2023-09-13 | GSE242965 | GEO
OtherMitochondrial translation termination, recycling, and rescue in in-frame and out-of-frame contexts
Originating from a bacterial ancestor, the mitochondrial mRNAs have unique characters, including noncanonical stop codons and polycistronic ORFs. However, the molecular mechanisms of how mitochondrial ribosomes terminate the translation and are recycled remain obscure. Harnessing the high-resolution...
ORGANISM(S): Homo sapiens Mus musculus 
2026-06-05 | GSE288420 | GEO
TranscriptomicsDeficiency of mitoribosomal S10 protein affects translation and splicing in Arabidopsis mitochondria
The ribosome is not only a protein-making machine, but also a regulatory element in protein synthesis. This view is supported by our earlier data showing that Arabidopsis mitoribosomes altered due to the silencing of the nuclear RPS10 gene encoding mitochondrial ribosomal protein S10 differentially ...
ORGANISM(S): Arabidopsis thaliana 
2019-10-29 | GSE132441 | GEO
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