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TranscriptomicsWhole genome profiling of liver sinusoidal endothelial cells (LSEC) before and after hepatectomy
compare acute gene expression changes in LSEC after hepatecomy WT C57BL/6N mice were either sham operated or underwent 2/3 hepatectomy. One day after operation, LSEC were isolated. RNA were immediatedly extracted for gene array.
ORGANISM(S): Mus musculus 
2013-08-26 | E-GEOD-50046 | biostudies-arrayexpress
TranscriptomicsNormal and injured liver sinusoidal endothelial cells
Comparison of C57BL/6J 8-10 weeks male mouse liver sinusoidal endothelial cells (LSEC) from normal liver and from liver injured by carbon tetrachloride administration. Keywords: other
ORGANISM(S): Mus musculus 
2004-10-01 | E-GEOD-1689 | biostudies-arrayexpress
TranscriptomicsLSEC: a microenvironment dependent differentiation program in rat including the novel junctional protein Leda-1
Liver sinusoidal endothelium (LSEC) is a prime example for organ-specific microvascular differentiation and functions. Disease-associated capillarization of LSEC in vivo and dedifferentiation of LSEC in vitro indicate the importance of the hepatic microenvironment. To identify the LSEC-specific mole...
ORGANISM(S): Rattus norvegicus 
2010-05-05 | E-GEOD-20375 | biostudies-arrayexpress
GenomicsChromatin Accessibility Changes Following NICD Overactivation in LSEC
Chromatin Accessibility Changes Following NICD Overactivation in LSEC
PRJNA1453960 | ENA
TranscriptomicsVEGF-A stimulated gene expression in human liver sinusoidal endothelial cells
Transcriptomic analysis of VEGF-A stimulated liver sinusoidal endothelial cell gene expression. Untreated cells were compared to those treated with VEGF-A. VEGF-A stimulation is critical for normal LSEC phenotype, and the response to liver injury Two conditions: untreated vs. VEGF-A treated. LSEC...
ORGANISM(S): Homo sapiens 
2013-06-01 | E-GEOD-41110 | biostudies-arrayexpress
GenomicsNext Generation Sequencing Facilitates Quantitative Analysis of LSEC and Hepa1-6 mono- and co-cultured
Next Generation Sequencing Facilitates Quantitative Analysis of LSEC and Hepa1-6 mono- and co-cultured
PRJNA836237 | ENA
UnknownCritical Role of LSEC in Post-Hepatectomy Liver Regeneration and Failure.
Not available
S-EPMC8347197 | biostudies-literature
UnknownIntestinal decontamination with rifaximin attenuates LSEC dysfunction and liver fibrosis in mice.
Not available
S-EPMC12829844 | biostudies-literature
Genomics
RNA sequence of LSEC
PRJNA1020559 | ENA
UnknownLncRNA Airn maintains LSEC differentiation to alleviate liver fibrosis via the KLF2-eNOS-sGC pathway.
Not available
S-EPMC9520944 | biostudies-literature
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