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Secretome analysis faces several challenges, including detection of low abundant proteins and the discrimination of bona fide secreted proteins from false-positive identifications stemming from cell leakage or serum. Here, we developed a two-step secretomics approach and applied it for the analysis ...
ORGANISM(S): Mus musculus (Mouse) 
2018-01-24 | PXD007527 | Pride
As an essential cellular component of the bone marrow (BM) microenvironment mesenchymal stromal cells (MSC) play a pivotal role for the physiological regulation of hematopoiesis, in particular through the secretion of cytokines and chemokines. Mass spectrometry (MS) facilitates the identification an...
ORGANISM(S): Homo sapiens (Human) 
2019-02-12 | PXD011643 | Pride
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