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MetabolomicsCharacterizing COPD phenotypes with a targeted signaling lipids metabolomics approach

A targeted metabolomics approach reveals distinct metabolic patterns associated with different GOLD stages, KNGF profiles and SYS subtypes in COPD patients, highlighting unique mechanisms and pathways underlying various COPD classification systems.

2025-07-21 | MTBLS11748 | MetaboLights
UnknownTruncation of the unique N-terminal domain improved the thermos-stability and specific activity of alkaline α-amylase Amy703.
Not available
S-EPMC4772547 | biostudies-literature
UnknownOptimization of whole-cell biotransformation for scale-up production of α-arbutin from hydroquinone by the use of recombinant Escherichia coli.
Not available
S-EPMC6598918 | biostudies-literature
ProteomicsCocaine-Induced Restructuring of the Rat Brain Peptidome: Quantitative Mass Spectrometry Reveals Anatomically Specific Patterns of Cocaine-Regulated Peptide Expression
Substance abuse, particularly cocaine, has detrimental effects on global public health, as acute intoxication often results in adverse outcomes and current pharmacological treatments exhibit limited effectiveness. The intricate process of cocaine intoxication involves substantial alterations in the ...
ORGANISM(S): Rattus norvegicus (Rat) 
2025-01-02 | PXD042363 | Pride
Rat Brain Peptidome Lc-ms/ms 
UnknownSingle chiral center epimerization-modulated multi-carrier-free oral hydrogel for remolding inflammatory microenvironment via PI3K/Akt/NF-κB and MAPK signaling pathways.
Not available
S-EPMC12546808 | biostudies-literature
UnknownEfficient expression of a novel <i>α</i>-amylase for reduction of tobacco starch and smoke hazard.
Not available
S-EPMC12283668 | biostudies-literature
ProteomicsHuman Plasma Gel Filtration Fractions MS Data
Mapping Atheroprotective Functions and Related Proteins/Lipoproteins in Size Fractionated Human Plasma
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
MSV000081547 | MassIVE
UnknownCB2R activation enhances tumor-associated macrophages-mediated phagocytosis of glioma cell.
Not available
S-EPMC11650289 | biostudies-literature
ProteomicsThe evolution of Proteomics in the genus Flaveria
C4 photosynthesis overpasses C3 by a higher photosynthetic rate, along with a higher water and nitrogen use efficiency. The establishment of C4 photosynthesis requires modification of ancestral C3 in both anatomical and metabolic aspects, both are involved in many functional pathways which have not ...
ORGANISM(S): Flaveria ramosissima 
2025-01-21 | PXD024720 | Pride
Flaveria C4 photosynthesis Evolution Proteomics 
MetabolomicsMMD collaborates with ACSL4 and MBOAT7 to promote polyunsaturated phosphatidylinositol remodeling and susceptibility to ferroptosis

Ferroptosis is a form of regulated cell death with roles in degenerative diseases and cancer. Excessive iron-catalyzed peroxidation of membrane phospholipids, especially those containing the polyunsaturated fatty acid arachidonic acid (AA), is central in driving ferroptosis. Here, we reveal that ...

2023-09-06 | MTBLS8280 | MetaboLights
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