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TranscriptomicsPromoter capture-C of primary HepG2 cells
We employed a massively parallel, high resolution Capture-C based method to simultaneously characterize the genome-wide interactions of all human promoters in any cell type. We applied this approach to study the promoter interactome of HepG2 cells (3 biological replicates). We designed a custom Agil...
ORGANISM(S): Homo sapiens 
2019-03-20 | E-MTAB-7144 | biostudies-arrayexpress
UnknownRandomized controlled trial: moxibustion and acupuncture for the treatment of Crohn's disease.
Not available
S-EPMC4138481 | biostudies-literature
ProteomicsLactylation of NAT10 promotes N4‐acetylcytidine modification on tRNASer-CGA-1-1 to boost oncogenic DNA virus KSHV reactivation
N4-acetylcytidine (ac4C), a conserved but recently rediscovered RNA modification on tRNAs, rRNAs and mRNAs, is catalyzed by N-acetyltransferase 10 (NAT10). Lysine acylation is a ubiquitous protein modification that controls protein functions. Our latest study demonstrates a NAT10-dependent ac4C modi...
ORGANISM(S): Homo Sapiens 
PXD049447 |
UnknownHematologic safety of 177Lu-PSMA-617 radioligand therapy in patients with metastatic castration-resistant prostate cancer.
Not available
S-EPMC8254689 | biostudies-literature
MetabolomicsHepatic Metabolomics Investigation in Acute and Chronic Murine Toxoplasmosis
Toxoplasma gondii poses a great threat to human health, with no approved vaccine available for the treatment of T. gondii infection. T. gondii infections are not limited to the brain, and may also affect other organs especially the liver. Identification of host liver molecules or pathways involved i...
2019-08-06 | MTBLS586 | MetaboLights
UnknownRapid and Efficient Radiosyntheses of Meta-substituted [F]Fluoroarenes from [F]Fluoride Ion and Diaryliodonium Tosylates within a Microreactor.
Not available
S-EPMC3195448 | biostudies-literature
TranscriptomicsProfiling circulating microRNA expression in a mouse model of nerve allotransplantation (part 2)
Background. The lack of noninvasive biomarkers of rejection remains a challenge in the accurate monitoring of deeply buried nerve allografts and precludes optimization of therapeutic intervention. This study aimed to establish the expression profile of circulating microRNAs (miRNAs) during nerve all...
ORGANISM(S): Mus musculus 
2014-07-01 | E-GEOD-48971 | biostudies-arrayexpress
TranscriptomicsA 3D molecular atlas of the chick embryonic heart
We performed a detailed analysis of gene expression in the 2-day (HH12) embryonic chick heart. RNA-seq of 13 microdissected heart regions reveals regionalised expression of about 15,000 genes (Dataset 1). Of these, 131 genes that are differentially expressed (FPKM ≥20, fold change ≥1.1-4.0) within a...
ORGANISM(S): Gallus gallus 
2019-10-02 | E-MTAB-7663 | biostudies-arrayexpress
TranscriptomicsProfiling circulating microRNA expression in a mouse model of nerve allotransplantation (part 1)
Background. The lack of noninvasive biomarkers of rejection remains a challenge in the accurate monitoring of deeply buried nerve allografts and precludes optimization of therapeutic intervention. This study aimed to establish the expression profile of circulating microRNAs (miRNAs) during nerve all...
ORGANISM(S): Mus musculus 
2014-07-01 | E-GEOD-48969 | biostudies-arrayexpress
UnknownNeutrophil membrane-coated therapeutic liposomes for targeted treatment in acute lung injury.
Not available
S-EPMC9365401 | biostudies-literature
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