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MetabolomicsThe bile acid metabolome in umbilical cord blood and meconium of healthy newborns: Distinct characteristics and implications (Umbilical cord blood analysis)

OBJECTIVE: To characterize the bile acid (BA) metabolomic profile of umbilical cord blood (UCB) and meconium in healthy newborns.

METHODS: Fifteen healthy newborns, which born in the Obstetrics Department of the Affiliated Hospital of Southwest Medical Univ...

2024-11-28 | MTBLS10266 | MetaboLights
MetabolomicsThe bile acid metabolome in umbilical cord blood and meconium of healthy newborns: Distinct characteristics and implications (Meconium analysis)

OBJECTIVE: To characterize the bile acid (BA) metabolomic profile of umbilical cord blood (UCB) and meconium in healthy newborns.

METHODS: Fifteen healthy newborns, which born in the Obstetrics Department of the Affiliated Hospital of Southwest Medical Univ...

2024-11-28 | MTBLS10267 | MetaboLights
UnknownPhosphoinositide-specific phospholipase Cγ1 inhibition induces autophagy in human colon cancer and hepatocellular carcinoma cells.
Not available
S-EPMC5654964 | biostudies-literature
TranscriptomicsEffect of Growth hormone on podocytes
Transcriptome analysis of growth hormone dependant genes in glomerular podocytes Differentiated human glomerular podocytes in culture exposed to growth hormone for 0 min, 2 min, 5 min, 15 min, and 30 min. Total RNA is extracted and subjected to microarray analysis.
ORGANISM(S): Homo sapiens 
2010-10-01 | E-GEOD-21327 | biostudies-arrayexpress
ProteomicsGABPA recruits the Integrator endonuclease complex to promote transcription elongation
Transcription factors (TFs) coordinate gene regulatory programs essential for cell identity, yet how individual TFs modulate distinct steps of transcription cycle remains incompletely understood. GA-binding protein alpha (GABPA), an erythroblast transformation specific (ETS)-family TF, is crucial fo...
ORGANISM(S): Mus musculus (Mouse) 
2026-08-04 | PXD068470 | Pride
Intac Gabpa Transcription elongation 
TranscriptomicsExpression Profiling of Avian Pathogenic E. coli WT and mutant
RNA-Seq was performed on Avian pathogenic E. coli (APEC) WT and mutant to investigate the pathogenicity of ArcA (Aerobic Respiratory Control), a global regulator important for E. coli’s adaptation from anaerobic to aerobic conditions and control of that bacterium’s enzymatic defenses against ROS.
ORGANISM(S): Escherichia coli K-12 
2017-03-01 | E-MTAB-3396 | biostudies-arrayexpress
ProteomicsProteomics and metabonomics analyses of Covid-19 complications in patients with pulmonary fibrosis
Pulmonary fibrosis is a devastating disease, and the pathogenesis of this disease is not completely clear. Here, the medical records of 85 Covid-19 cases were collected, among which fibrosis and progression of fibrosis were analyzed in detail. Next, data independent acquisition (DIA) quantification ...
ORGANISM(S): Homo Sapiens 
2021-02-22 | PXD024311 |
ProteomicsThe Glomerulus Multi-Omics Analysis Provides Deeper Insights into Diabetic Nephropathy
Diabetic nephropathy (DN) is the leading cause of end-stage renal disease (ESRD), however, the detail mechanisms remain unclear. Here, we integrated the transcriptomics and proteomics profiles of glomeruli isolated from 50 biopsy-proven DN patients and 25 controls to explore the new discoveries unde...
ORGANISM(S): Homo Sapiens 
2023-03-06 | PXD040617 |
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