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ProteomicsGlobal Spinal Cord Peptidome Profiling in Response to Osteoarthritis in Rats
Osteoarthritis (OA) is a complex and increasingly prevalent condition affecting an estimated 600 million people worldwide, significantly diminishing quality of life. Understanding OA as both an inflammatory and neurological disease presents challenges for treatment, with no approved disease-modifyin...
ORGANISM(S): Rattus norvegicus (Rat) 
2025-10-28 | PXD060558 | Pride
Pain Mi-rat Osteoarthritis Mass spectrometry Neuropeptide Peptidome 
ProteomicsCocaine-Induced Restructuring of the Rat Brain Peptidome: Quantitative Mass Spectrometry Reveals Anatomically Specific Patterns of Cocaine-Regulated Peptide Expression
Substance abuse, particularly cocaine, has detrimental effects on global public health, as acute intoxication often results in adverse outcomes and current pharmacological treatments exhibit limited effectiveness. The intricate process of cocaine intoxication involves substantial alterations in the ...
ORGANISM(S): Rattus norvegicus (Rat) 
2025-01-02 | PXD042363 | Pride
Rat Brain Peptidome Lc-ms/ms 
ProteomicsNeuropeptidomics of the American Lobster Homarus americanus
The American lobster, Homarus americanus, is not only of considerable economic importance but has also emerged as a pivotal model in neuroscience research. Neuropeptides, an important class of cell-to-cell signaling molecules, play crucial roles in a wide array of physiological and psychological pro...
ORGANISM(S): Homarus americanus 
2024-04-27 | PXD047230 | Pride
American lobster Mass spectrometry Neuropeptide Peptidome 
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