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MetabolomicsHyocholic acid species as novel biomarkers for metabolic disorders
Hyocholic acid (HCA) is a major bile acid (BA) species in the BA pool of pigs, a species known for its exceptional resistance to spontaneous development of diabetic phenotypes. HCA and its derivatives are also present in human blood and urine. We investigate whether human HCA profiles can predict th...
2021-10-06 | MTBLS2343 | MetaboLights
UnknownPhotoactivation mechanism of a carotenoid-based photoreceptor.
Not available
S-EPMC5474822 | biostudies-literature
ProteomicsProtein acetylation landscape of developing rice anthers
Protein lysine acetylation (KAC) is a dynamic and reversible post-translational modification, playing important biological roles in many organisms.Here, we reported results from a proteomic investigation to detect KAC status of the developing rice anthers near the time of meiosis (RAM), providing st...
ORGANISM(S): Oryza sativa (Rice) 
2019-03-06 | PXD007986 | Pride
Lc-msms Lysine acetylation Anther development Meiosis Rice 
MetabolomicsDT-109 ameliorates nonalcoholic steatohepatitis in nonhuman primates

Nonalcoholic steatohepatitis (NASH) prevalence is rising with no pharmacotherapy approved. A major hurdle in NASH drug development is the poor translatability of preclinical studies to safe/effective clinical outcomes, and recent failures highlight a need to identify new targetable pathways. Dysr...

2023-04-13 | MTBLS5005 | MetaboLights
UnknownA non-canonical role of the inner kinetochore in regulating sister-chromatid cohesion at centromeres
Not available
S-SCDT-10_1038-S44318-024-00104-6 | biostudies-other
ProteomicsTotal and mitochondrial transcriptomic and proteomic insights into energy regulation mechanism for shoot fast growth initiation in Moso bamboo(Phyllostachys edulis)
Moso bamboo (Phyllostachys edulis) is one of the fast-growing plant species and has high comprehensive utilization value. However, how Moso bamboo realize the transition from initial growth of winter shoot to fast growth of spring shoot is still unknown. Large increase of biomass in spring shoot sug...
ORGANISM(S): Phyllostachys Edulis 
2021-08-30 | PXD028178 |
ProteomicsLC-MS/MS-based metabolomics and proteomics reveal the intervention of Kangnian Decoction on the postoperative intestinal adhesion of rats
This study aims to explore the therapeutic effects of KN decoction in a PIA rat model, as well as its potential mechanisms via metabolomics and proteomics analyses.
ORGANISM(S): Rattus Norvegicus 
2024-09-09 | PXD055723 |
ProteomicsPan-analysis of Single Amino-acid Polymorphism
Uncovering dark mass in population proteomics: Pan-analysis of Single Amino-acid Polymorphism (Pan-SAP) revealed quantitative relevance with cognition and aging
ORGANISM(S): Homo Sapiens 
2024-12-31 | PXD059327 |
ProteomicsNovel phenotypes of immune-mediated necrotizing myopathy identified independent of myositis-specific antibody specificity that improve prognostic stratification
Immune-mediated necrotizing myopathy (IMNM) is a severe autoimmune myopathy with high clinical heterogeneity. Current classification relies on myositis-specific antibodies (MSA: anti-HMGCR, anti-SRP) but fails to explain differences in manifestations, interstitial lung disease (ILD) incidence, and s...
ORGANISM(S): Homo Sapiens 
2026-05-06 | PXD078154 |
ProteomicsProteomics-based mechanistic investigation of Escherichia coli inactivation by pulsed electric field
mechanistic investigation of Escherichia coli inactivation
ORGANISM(S): Escherichia Coli Vdp 
2019-06-25 | PXD014365 |
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