Lubac - OmicsDI

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The linear ubiquitin chain assembly complex LUBAC generates heterotypic ubiquitin chains

The linear ubiquitin chain assembly complex (LUBAC) is the only known ubiquitin ligase that generates linear/Met1-linked ubiquitin chains. One of the LUBAC components, HOIL-1L, was recently shown to catalyse oxyester bond formation between the C-terminus of ubiquitin and some substrates. However, ox...

ORGANISM(S): Homo sapiens (Human)

2021-06-28 | PXD019771 | Pride

E3 ubiquitin ligase/ ester-bond linkage/ hoil-1l/ rbr/ ubiquitin

SPATA2 Links CYLD to LUBAC, Activates CYLD, and Controls LUBAC Signaling.

Not available

S-EPMC5031558 | biostudies-literature

Molecular basis and regulation of OTULIN-LUBAC interaction.

Not available

S-EPMC4017264 | biostudies-literature

LUBAC interactors identification

Identification of LUBAC interactors. Analysis of HOIL-1, HOIP and Sharpin N and C terminal interactors

ORGANISM(S): Homo sapiens (Human)