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TranscriptomicsTranscription profiling of human umbilical vein endothelial cells (HUVECs) transduced with pMLV-MCS or pMLV-THAP1 retroviral expression vectors
Goal of the experiment : Retroviral-mediated gene transfer of the THAP-zinc finger protein THAP1 inhibits endothelial cell proliferation through coordinated repression of critical cell cycle regulators and pRB-E2F target genes. Experimental design: To gain insight into the effects of THAP1 on endo...
ORGANISM(S): Homo sapiens 
2006-09-11 | E-TABM-24 | biostudies-arrayexpress
TranscriptomicsExpression profiling of 40 NSCLC cell lines
INTRODUCTION: CDKN2A (p16) inactivation is common in lung cancer and occurs via homozygous deletions, methylation of promoter region, or point mutations. Although p16 promoter methylation has been linked to KRAS mutation and smoking, the associations between p16 inactivation mechanisms and other com...
ORGANISM(S): Homo sapiens 
2015-06-22 | E-GEOD-63882 | biostudies-arrayexpress
UnknownTreatment Response Score to Glatiramer Acetate or Interferon Beta-1a.
Not available
S-EPMC7905777 | biostudies-literature
GenomicsDistinct Function for ASCL1 and NEUROD1 in Pulmonary Neuroendocrine Tumors (ChIP-seq)
Small cell lung carcinoma (SCLC) and large cell neuroendocrine carcinoma (LCNEC) are high-grade pulmonary neuroendocrine tumors. The neural basic helix-loop-helix (bHLH) transcription factors ASCL1 and NEUROD1 have been shown to play crucial roles in promoting the malignant behavior and survival of ...
ORGANISM(S): Mus musculus 
2016-07-21 | E-GEOD-69394 | biostudies-arrayexpress
UnknownAssociation of Inflammation and Disability Accrual in Patients With Progressive-Onset Multiple Sclerosis.
Not available
S-EPMC6248114 | biostudies-literature
UnknownA Bundle of Interventions to Prevent Pressure Ulcers During Prone Position in Adult Patients With Acute Respiratory Distress Syndrome: Results of a French Stepped-Wedge Randomized Controlled Trial.
Not available
S-EPMC12163295 | biostudies-literature
UnknownAssociation of Sustained Immunotherapy With Disability Outcomes in Patients With Active Secondary Progressive Multiple Sclerosis.
Not available
S-EPMC7385679 | biostudies-literature
TranscriptomicsMethylation profiling of human NSCLC promoter regions identifies novel methylation markers for multiple malignancies
BACKGROUND: Promoter hypermethylation coupled with loss of heterozygosity at the same locus results in loss of gene function in many tumor cells. The "rules" governing which genes are methylated during the pathogenesis of individual cancers, how specific methylation profiles are initially establishe...
ORGANISM(S): Homo sapiens 
2008-06-15 | E-GEOD-6695 | biostudies-arrayexpress
UnknownFirst-year treatment response predicts the following 5-year disease course in patients with relapsing-remitting multiple sclerosis.
Not available
S-EPMC12014414 | biostudies-literature
UnknownPersistent progression independent of relapse activity in multiple sclerosis.
Not available
S-EPMC12405762 | biostudies-literature
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