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MetabolomicsUntargeted LC-HRMS Based-Plasma Metabolomics Reveals 3-O-Methyldopa as a New Biomarker of Poor Prognosis in High-Risk Neuroblastoma
Neuroblastoma (NB) is the most common extracranial malignant tumor in children. Although the survival rate of NB has improved over the years, the outcome of NB still remains poor for over 30% of cases. A more accurate risk stratification remains a key point in the study of NB and the availability of...
2023-07-14 | MTBLS4294 | MetaboLights
ModelsCapuani2015 - Binding of Cbl and Grb2 to EGFR (Early Activation Model - EAM)
Fabrizio Capuani, Alexia Conte, Elisabetta Argenzio, Luca Marchetti, Corrado Priami, Simona Polo, Pier Paolo Di Fiore, Sara Sigismund & Andrea Ciliberto. Quantitative analysis reveals how EGFR activation and downregulation are coupled in normal but not in cancer cells. Nature Communications 6 (2015)...
2024-09-02 | BIOMD0000000595 | BioModels
ModelsCapuani2015 - Binding of Cbl and Gbr2 to EGFR (Multisite Phosphorylation Model - MPM)
Fabrizio Capuani, Alexia Conte, Elisabetta Argenzio, Luca Marchetti, Corrado Priami, Simona Polo, Pier Paolo Di Fiore, Sara Sigismund & Andrea Ciliberto. Quantitative analysis reveals how EGFR activation and downregulation are coupled in normal but not in cancer cells. Nature Communications 6 (2015)...
2024-09-02 | BIOMD0000000594 | BioModels
MetabolomicsMetabolic profiling of Candida clinical isolates of different species and infection sources

Candida species are the most common cause of opportunistic fungal infections. Rapid identification and novel approaches for the characterization of these fungi are of great interest to improve the diagnosis and the knowledge about their pathogenic properties. This study aimed to characte...

2024-07-09 | MTBLS1978 | MetaboLights
TranscriptomicsTranscription profiling of mouse myotubes infected with PGCalpha
Various studies have shown that aerobic exercise can prevent or alleviate cancer-induced muscle wasting. To reproduce at least partially in vitro some molecular differences of aerobic muscle exercise that are independent from systemic inflammation or the hormonal milieu, we infected fully different...
ORGANISM(S): Mus musculus 
2019-11-17 | E-MTAB-8457 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of leukemia samples prepared using different RNA isolation procedures
Microarray gene expression (MAGE) signatures allow insights into the transcriptional processes of leukemias and may evolve as a molecular diagnostic test. Introduction of MAGE into clinical practice of leukemia diagnosis will require comprehensive assessment of variation due to the methodologies. Fo...
ORGANISM(S): Homo sapiens 
2008-11-06 | E-GEOD-7757 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of human CD43+ cells isolated from myelodysplastic syndrome patients and normal controls reveals involvement of interferon-stimulated genes and correlation to FAB subtype and karyotype.
55 patients with MDS and 11 healthy controls were included in the study. At the time of investigation, 18 patients had RA, 19 RARS and 18 RAEB. The RAEB group was further subdivided into RAEB1 and RAEB2 for a selected part of the analysis. Bone marrow samples were obtained and CD34+ cells isolated f...
ORGANISM(S): Homo sapiens 
2007-10-26 | E-GEOD-4619 | biostudies-arrayexpress
UnknownClinical performance of lung ultrasound in predicting time-dependent changes in lung aeration in ARDS patients.
Not available
S-EPMC9358118 | biostudies-literature
MetabolomicsThe measurement of spatial distribution of grape metabolites in berry tissues using LC-MS
The study aims to describe the differential spatial distrubution of secondary metabolites in different grape species,. The aims is to describe the characteristics that differentiate wild grapes from good quality vinifera grapes, understand the limits and advantages from both classes.
2017-01-23 | MTBLS209 | MetaboLights
MetabolomicsAberrant L-Fucose accumulation and increased core fucosylation are metabolic liabilities in mesenchymal glioblastoma (Xenograft assays)

Glioblastoma (GBM) is a common and deadly form of brain tumor in adults. Dysregulated metabolism in GBM offers an opportunity to deploy metabolic interventions as precise therapeutic strategies. To identify the molecular drivers and the modalities by which different molecular subgroups of GBM exp...

2022-11-08 | MTBLS730 | MetaboLights
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